TABLE 4
FROM:
Chromosomal analysis of non-small-cell lung cancer by multicolour fluorescent in situ hybridisation
H K Berrieman, J N E Ashman, M E Cowen, J Greenman, M J Lind and L Cawkwell
BACK TO ARTICLETable 4. Common regions of gain and loss of DNA sequences (including minimal regions of overlap) in primary tumour samples and cell lines observed by CGH
| Region | Primary tumour (n=3) | Cell line (n=2) | Total (n=5) | Minimal region of overlap |
|---|---|---|---|---|
| Gain | ||||
| 5p | 3 | 2 | 5 | p11–p13a |
| 3q | 2 | 2 | 4 | q13.3–q25 |
| 8q | 2 | 2 | 4 | q23 |
| 11q | 2 | 2 | 4 | q13 |
| 2q | 2 | 1 | 3 | q22–q24 |
| 12p | 1 | 2 | 3 | p11.1–p11.2 |
| 12q | 1 | 2 | 3 | q21 |
| Loss | ||||
| 9p | 3 | 2 | 5 | p23 |
| 3p | 2 | 2 | 4 | p24–p25 |
| 6q | 2 | 2 | 4 | q25–qter |
| 17p | 2 | 2 | 4 | p11.1–p12 |
| 22q | 2 | 2 | 4 | q13 |
| 8p | 2 | 1 | 3 | p21–p22 |
| 10p | 2 | 1 | 3 | p13 |
| 10q | 2 | 1 | 3 | q25–qter |
| 19p | 2 | 1 | 3 | p13.2 |
a Four out of five samples (including two observed by M-FISH to have iso5p) showed gains of the entire 5p arm.
