British Journal of Cancer

TABLE 6

FROM:

Diagnostic accuracy for different strategies of image-guided breast intervention in cases of nonpalpable breast lesions

R M Pijnappel, M van den Donk, R Holland, W P Th M Mali, J L Peterse, J H C L Hendriks and P H M Peeters

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Table 6. Agreement rate, underestimate and overestimate rates for the different primary diagnostic procedures

 Surgical biopsyFNA US-guidedLCNB US-guidedLCNB stereotacticCOBRA study
Needle (gauge) 22G18G+14G14G14G
n=3161488954858
Nonconclusive (%)1.229431.5
Agreement rate (%)Not applicable87868593
Miss rate (%)251283
Sensitivity (%)9895889297
High risk underestimate rate (%)a 9Not applicable334023
DCIS underestimate rate (%)b 8Not applicable372717
DCIS overestimate rate (%)c Not applicable9Not applicableNot applicableNot applicable

a High-risk underestimate is defined as the finding of ADH, lobular carcinoma in situ without malignancy in the diagnostic material, but with carcinoma (in situ or invasive), in the surgical specimen

b DCIS underestimate is defined as the finding of DCIS without invasive carcinoma in the diagnostic material, but with invasive carcinoma in the therapeutical specimen

c DCIS overestimate is defined as the finding of malignant cells on cytology and DCIS without invasive carcinoma in the surgical specimen. US-guided=ultrasound guided.

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