British Journal of Cancer

FIGURE 3

FROM:

COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ

G P Boland, I S Butt, R Prasad, W F Knox and N J Bundred

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Figure 3.

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(A) DCIS showing minimal COX-2 expression with scanty brown cytoplasmic immunostaining (score 1+, classified as COX-2 negative), (B) moderate COX-2 staining with approximately 5060% of cells strongly stained (score 2+, classified as COX-2 positive), (C) High COX-2 expression in cribriform DCIS with 100% of cells intensely stained (score 3+, classified as COX-2 positive), (D) HER-2 staining in DCIS: note the strong membranous staining (score 3+, classified HER-2 positive).

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