British Journal of Cancer

FIGURE 2

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Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB

A S Whitehouse and M J Tisdale

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Figure 2.

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Effect of PIF on the chymotrypsin-like enzyme activity in C2C12 myotubes in the absence (black boxes) or presence (grey boxes) of 50 mu M EPA (grey boxes). The data are expressed as meanplusminuss.e.m. where n=9 and the values represent the activity inhibited by 10 mu M lactacystin. The differences from control are indicated as a, P<0.05 and b, P<0.001, while differences in the presence of EPA are indicated as c, P<0.05 and d, P<0.001.

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