British Journal of Cancer - Figure 1 for article: Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-[kappa]B

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Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-B

A S Whitehouse and M J Tisdale

Figure 1.

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Effect of PIF in the absence (black boxes) or presence (grey boxes) of lactacystin (10 M) on protein degradation in C₂C₁₂ myotubes as determined by [³H] phenylalanine release. Lactacystin was present for 2 h prior to PIF and was also present throughout the 24 h incubation period. All values have been normalised to their respective controls and the experiment was repeated twice, n=3 for each treatment. The data are expressed as mean plusminus s.e.m. and was measured 24 h after the addition of PIF. Differences from control are indicated as a, P<0.01 and b, P<0.001, while differences in the presence of lactacystin are shown as c, P<0.001.

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FIGURE 1

Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-B

Figure 1.