British Journal of Cancer

TABLE 1

FROM:

Combination chemotherapy in advanced gastrointestinal cancers: ex vivo sensitivity to gemcitabine and mitomycin C

P A Whitehouse, S J Mercer, L A Knight, F Di Nicolantonio, A O'Callaghan and I A Cree on behalf of the Portsmouth Upper GI and Colorectal Cancer Multidisciplinary Teams

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Table 1. Summary of sensitivity data (using an arbitrary threshold of sensitivity defined as a IndexSUM<300 for six concentrations used)

Drug No. assessed No. sensitive Sensitivity (%) (Index <300) >95% Inhibition (%)
Oesophagogastric cancer
 Mitomycin C21157114 (three out of 21)
 Gemcitabine177426 (one out of 17)
 Mitomycin C+Gemcitabine131310038 (five out of 13)
 
Colorectal cancer
 Mitomycin C39215410 (four out of 39)
 Gemcitabine3819503 (one out of 38)
 Mitomycin C+gemcitabine353510060 (21 out of 35)
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