TABLE 2

FROM:

Cytology vs molecular analysis for the detection of head and neck squamous cell carcinoma in oesopharyngeal brush samples: a prospective study in 56 patients

S Temam, M Trassard, G Leroux, J Bosq, B Luboinski, G Lenoir, J Bénard and F Janot

Table 2. p53 mutations in 31 patients with HNSCC

Patients no.	Exon	Codona	Sequence	Amino acid
28	4	35	Deletion 1 bp	Frameshift
35	4	111	CTG CAG	L Q
18	5	125	ACG AGG	T R
27	5	126	TAC TGC	Y C
31	5	134	TTT GTT	F V
30	5	146	TGG TAG	W Stop
36	5	179	CAT CTT	H L
34	5	183	TCA TGA	S Stop
3	5	187	GGT GTT	G V
1	6	193	CAT CTT	H L
12	6	204	GAG TAG	E Stop
7	7	245	GGC GAC	G V
2	7	247	AAC AAT	N N
24	7	248	CGC CTG	R L
19	7	248	CGG CAG	R L
15	7	257	Insertion 1 bp	Frameshift
26	8	270	TTT TCT	F S
32, 33, 20	8	273	CGT TGT	R C
14	8	273	CGT CAT	R H
23	8	275	TGT TTT	C F
4, 29, 17, 21	8	282	CGG TGG	R W
5	9	319	AAG TAG	K Stop
16	9	321	Deletion 1 bp	Frameshift
25	9	331	CAG TAG	Q Stop
6	9	327 or 328	Insertion 1 bp	Frameshift
22	10	Intron 11	17708 A T	Silent

^a First codon of the frameshift mutation.

 bp=base pair.