British Journal of Cancer

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Thiram inhibits angiogenesis and slows the development of experimental tumours in mice

M Marikovsky

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Figure 1.

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TR inhibits DNA synthesis in various cell types. DNA synthesis was measured by the incorporation of [3H]-thymidine into the cells, as described in Materials and Methods. TR at various concentrations was incubated with BCE, BSMC, BALB/MK, C6 rat glioma cells and with D122 cells as described in Materials and Methods. TR inhibited in a dose-dependent manner DNA synthesis in various cell types. Experiments were done in triplicates and inhibition was calculated as percentage of DNA synthesis of non-treated control.

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