TY  - JOUR
AU  - Aebi, S.
AU  - Assereto, R.
AU  - Lauterburg, B. H.
TI  - High-dose intravenous glutathione in man. Pharmacokinetics and effects on cyst(e)ine in plasma and urine
JA  - Eur J Clin Invest
PY  - 1991///
VL  - 21
SP  - 103
EP  - 110
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Alberts, D. S.
AU  - Noel, J. K.
TI  - Cisplatin associated neurotoxicity, can it be prevented?
JA  - Anticancer Drugs
PY  - 1995///
VL  - 6
SP  - 369
EP  - 383
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Alberts, D. S.
AU  - Liu, P. Y.
AU  - Hanigan, E. V.
AU  - O/'Toole, R.
AU  - Williams, S. D.
AU  - Young, J. A.
AU  - Franklin, E. W.
AU  - Clarke-Pearson, D. L.
AU  - Malviya, V. K.
AU  - Dubeshter, B.
AU  - Adelson, M. D.
AU  - Hoskins, W. J.
TI  - Intraperitoneal cisplatin plus intravenous cyclophosphamide versus intravenous cisplatin plus intravenous cyclophosphamide for stage III ovarian cancer
JA  - N Engl J Med
PY  - 1996///
VL  - 335
SP  - 1950
EP  - 1956
PB  - Cancer Research Campaign
M3  - 10.1056/NEJM199612263352603
N1  - 10.1056/NEJM199612263352603
UR  - http://dx.doi.org/10.1056/NEJM199612263352603
ER  - 

TY  - JOUR
AU  - Ben-Josef, E.
AU  - Mesina, J.
AU  - Shaw, L. M.
AU  - Bonner, H. S.
AU  - Shamsa, F.
AU  - Porter, A. T.
TI  - Topical application of WR-2721 achieves high concentrations in the rectal wall
JA  - Radiation Res
PY  - 1995///
VL  - 143
SP  - 107
EP  - 110
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Betticher, D. C.
AU  - Anderson, H.
AU  - Ranson, M.
AU  - Meeley, K.
AU  - Oster, W.
AU  - Thatcher, N.
TI  - Carboplatin combined with amifostine, a bone marrow protectant, in the treatment of non-small cell lung cancer. A randomized phase II study
JA  - Br J Cancer
PY  - 1995///
VL  - 72
SP  - 1551
EP  - 1555
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Bogliun, G.
AU  - Marzorati, L.
AU  - Marzola, M.
AU  - Miceli, M. D.
AU  - Cantu, M. G.
AU  - Cavaletti, G.
TI  - Neurotoxicity of cisplatin +/- reduced glutathione in the first-line treatment of advanced ovarian cancer
JA  - Int J Gynaecol Cancer
PY  - 1996///
VL  - 6
SP  - 415
EP  - 419
PB  - Cancer Research Campaign
M3  - 10.1046/j.1525-1438.1996.06050415.x
N1  - 10.1046/j.1525-1438.1996.06050415.x
UR  - http://dx.doi.org/10.1046/j.1525-1438.1996.06050415.x
ER  - 

TY  - JOUR
AU  - Brizel, D.
AU  - Sauer, M.
AU  - Wannenmacher, M.
AU  - Henke, M.
AU  - Eschwege, F.
AU  - Wasserman, T.
TI  - Randomized phase III trial of radiation +/- amifostine in patients with head and neck cancer
JA  - Proc Am Soc Clin Oncol
PY  - 1998///
VL  - 17
SP  - 
EP  - 
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Budd, G. T.
TI  - Amifostine and chemotherapy-related thrombocytopenia
JA  - Semin Oncol
PY  - 1996///
VL  - 23
SP  - 49
EP  - 52
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Budd, G. T.
AU  - Bukowski, R. M.
AU  - Adelstein, D.
AU  - Pelley, R.
AU  - Olencki, T.
AU  - Petrus, J. V.
AU  - McLain, D.
AU  - Conlon, J.
AU  - Kurman, M.
AU  - Capizzi, R. L.
AU  - Ganapathi, R.
TI  - Mature results of a randomized trial of carboplatin and amifostine vs carboplatin alone in patients with advanced malignancies
JA  - Proc Am Soc Clin Oncol
PY  - 1996///
VL  - 15
SP  - 
EP  - 
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Buntzel, J.
AU  - Kuttner, K.
AU  - Frohlich, D.
AU  - Glatzel, M.
TI  - Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer
JA  - Ann Oncol
PY  - 1998///
VL  - 9
SP  - 505
EP  - 509
PB  - Cancer Research Campaign
M3  - 10.1023/A:1008282412670
N1  - 10.1023/A:1008282412670
UR  - http://dx.doi.org/10.1023/A:1008282412670
ER  - 

TY  - JOUR
AU  - Calabro-Jones, P. M.
AU  - Fahey, R. C.
AU  - Smoluk, G. D.
AU  - Ward, J. F.
TI  - Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721
JA  - Int J Radiat Biol
PY  - 1985///
VL  - 47
SP  - 23
EP  - 27
PB  - Cancer Research Campaign
M3  - 10.1080/09553008514550041
N1  - 10.1080/09553008514550041
UR  - http://dx.doi.org/10.1080/09553008514550041
ER  - 

TY  - JOUR
AU  - Calabro-Jones, P. M.
AU  - Aguilera, J. A.
AU  - Ward, J. F.
AU  - Smoluk, G. D.
AU  - Fahey, R. C.
TI  - Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug
JA  - Cancer Res
PY  - 1988///
VL  - 48
SP  - 3634
EP  - 3640
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Capizzi, R. L.
AU  - Oster, W.
TI  - Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine: clinical experience
JA  - Eur J Cancer
PY  - 1995///
VL  - 31A
SP  - 8
EP  - 13
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Delaney, J. P.
AU  - Bonsack, M. E.
AU  - Felemovicius, I.
TI  - Radioprotection of the rat small intestine with topical WR-2721
JA  - Cancer
PY  - 1994///
VL  - 74
SP  - 2379
EP  - 2384
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - De Wit, R.
TI  - Four cycles of BEP versus an altering regime of PVB and BEP in patients with poor prognosis metastatic testicular non-seminoma. A randomised study of the EORTC Genitourinary Tract Cancer Cooperative Group
JA  - Br J Cancer
PY  - 1995///
VL  - 71
SP  - 1311
EP  - 1314
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - DiPaola, R. S.
AU  - Rodriguez, R.
AU  - Goodin, S.
AU  - Recio, A.
AU  - Orlick, M.
AU  - Mollman, J.
AU  - Bird, S.
AU  - Belsh, J. M.
AU  - Schein, P. S.
AU  - Aisner, J.
AU  - Schuchter, L. M.
TI  - Amifostine and dose-intense paclitaxel in patients with advanced malignancies
JA  - Cancer Therapeutics
PY  - 1998///
VL  - 1
SP  - 11
EP  - 17
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Di Re, F.
AU  - Bohm, S.
AU  - Oriana, S.
AU  - Spatti, G. B.
AU  - Zunino, F.
TI  - Efficacy and safety of high-dose cisplatin and cyclophosphamide with glutathione protection in the treatment of bulky advanced epithelial ovarian cancer
JA  - Cancer Chemother Pharmacol
PY  - 1990///
VL  - 25
SP  - 355
EP  - 360
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Di Re, F.
AU  - Bohm, S.
AU  - Oriana, S.
AU  - Spatti, G. B.
AU  - Pirovano, C.
AU  - Tedeschi, M.
AU  - Zunino, F.
TI  - High-dose cisplatin and cyclophosphamide with glutathione in the treatment of advanced ovarian cancer
JA  - Ann Oncol
PY  - 1993///
VL  - 4
SP  - 55
EP  - 61
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Dorr, R. T.
TI  - Cytoprotective agents for anthracyclines
JA  - Semin Oncol
PY  - 1996///
VL  - 23
SP  - 23
EP  - 24
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Douay, L.
AU  - Hu, C.
AU  - Giarratana, M-C
AU  - Bouchet, S.
AU  - Conlon, J.
AU  - Capizzi, R. L.
AU  - Gorin, N-C
TI  - Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging
JA  - Blood
PY  - 1995///
VL  - 86
SP  - 2849
EP  - 2855
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Dunn, T. A.
AU  - Schmoll, H. J.
AU  - Grunwald, V.
AU  - Bokemeyer, C.
AU  - Casper, J.
TI  - Amifostine does not alter the antitumor activity of cisplatin in a pre-clinical model of testicular cancer
JA  - Anticancer Drugs
PY  - 1996///
VL  - 7
SP  - 795
EP  - 799
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Ercan, M. T.
AU  - Aras, T.
AU  - Aktas, A.
AU  - Kaya, S.
AU  - Bekdik, C. F.
TI  - Accumulation of 99mTc-glutathione in head and neck tumors
JA  - Nuklearmedizin
PY  - 1994///
VL  - 33
SP  - 224
EP  - 228
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Glick, J. H.
AU  - Glover, D. J.
AU  - Weiler, C.
TI  - Phase I controlled trials of WR-2721 and cyclophosphamide
JA  - Int J Oncol Biol Phys
PY  - 1984///
VL  - 10
SP  - 1777
EP  - 1780
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Glover, D.
AU  - Glick, J. H.
AU  - Weiler, C.
AU  - Fox, K.
AU  - Turrisi, A.
AU  - Klingerman, M. M.
TI  - Phase I/II trials of WR-2721 and cis-platinum
JA  - Int J Radiat Oncol Biol Phys
PY  - 1986///
VL  - 12
SP  - 1509
EP  - 1512
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Grdina, D. J.
AU  - Kataoka, Y.
AU  - Basic, I.
TI  - The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation
JA  - Carcinogenesis
PY  - 1992///
VL  - 13
SP  - 811
EP  - 813
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Grdina, D. J.
AU  - Shigematsu, N.
AU  - Dale, P.
AU  - Nemton, G. L.
AU  - Aguilera, J. A.
AU  - Fahey, R. C.
TI  - Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action
JA  - Carcinogenesis
PY  - 1995///
VL  - 16
SP  - 767
EP  - 774
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Gyenes, G.
AU  - Fornander, T.
AU  - Carlens, P.
AU  - Skovsgaard, T.
TI  - Morbidity of ischemic heart disease in early breast cancer 15-20 years after adjuvant radiotherapy
JA  - Int J Rad Oncol Biol Phys
PY  - 1996///
VL  - 28
SP  - 1235
EP  - 1241
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Hamers, F. P. T.
AU  - Brakkee, J. H.
AU  - Cavalletti, E.
AU  - Tedeschi, M.
AU  - Marmonti, L.
AU  - Pezzoni, G.
AU  - Neijt, J. P.
AU  - Gispen, W. H.
TI  - Reduced glutathione protects against cisplatin-induced neurotoxicity in rats
JA  - Cancer Res
PY  - 1993///
VL  - 53
SP  - 544
EP  - 549
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Hill, C. K.
AU  - Nagy, B.
AU  - Persaino, C.
TI  - WR-2721 is anti-neoplastic and anti-mutagenic when given during 60Co [ggr]-ray irradiation
JA  - Carcinogenesis
PY  - 1986///
VL  - 7
SP  - 665
EP  - 668
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Kaltenbach, J. A.
AU  - Church, M. W.
AU  - Blakley, B. W.
AU  - McCaslin, D. L.
AU  - Burgio, D. L.
TI  - Comparison of five agents in protecting the cochlea against the ototoxic effects of cisplatin in the hamster
JA  - Otolaryngol Head Neck Surg
PY  - 1997///
VL  - 117
SP  - 493
EP  - 500
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Kataoka, Y.
AU  - Basic, I.
AU  - Perrin, J.
TI  - Antimutagenic effects of radioprotector WR-2721 against fission spectrum neutrons and 60Co [ggr]-rays in mice
JA  - Int J Radiat Biol
PY  - 1992///
VL  - 61
SP  - 387
EP  - 392
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Kemp, G.
AU  - Rose, P.
AU  - Lurain, J.
AU  - Berman, M.
AU  - Manetta, A.
AU  - Roullet, B.
AU  - Homesley, H.
AU  - Belpomme, D.
AU  - Glick, J.
TI  - Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized controlled trial in patients with advanced ovarian cancer
JA  - J Clin Oncol
PY  - 1996///
VL  - 14
SP  - 2101
EP  - 2112
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Korst, A. E. C.
AU  - Eeltink, C. M.
AU  - Vermorken, J. B.
AU  - Van de Vijgh, W. J. F.
TI  - Pharmacokinetics of amifostine and its metabolites in patients
JA  - Eur J Cancer
PY  - 1997///
VL  - 33
SP  - 1425
EP  - 1429
PB  - Cancer Research Campaign
M3  - 10.1016/S0959-8049(97)00138-X
N1  - 10.1016/S0959-8049(97)00138-X
UR  - http://dx.doi.org/10.1016/S0959-8049(97)00138-X
ER  - 

TY  - JOUR
AU  - Leone, R.
AU  - Fracasso, M. E.
AU  - Soresi, E.
AU  - Cimino, G.
AU  - Tedeschi, M.
AU  - Castoldi, D.
AU  - Monzani, V.
AU  - Colombi, L.
AU  - Usari, T.
AU  - Bernareggi, A.
TI  - Influence of glutathione administration on the disposition of free and total platinum in patients after administration of cisplatin
JA  - Cancer Chemother Pharmacol
PY  - 1992///
VL  - 29
SP  - 385
EP  - 390
PB  - Cancer Research Campaign
M3  - 10.1007/BF00686008
N1  - 10.1007/BF00686008
UR  - http://dx.doi.org/10.1007/BF00686008
ER  - 

TY  - JOUR
AU  - Lipschulz, S. E.
AU  - Colan, S. D.
AU  - Gelber, R. D.
AU  - Peres-Atayde, A. R.
AU  - Sallan
AU  - Sanders, S. P.
TI  - Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukaemia in childhood
JA  - N Engl J Med
PY  - 1991///
VL  - 324
SP  - 808
EP  - 815
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - List, A. F.
AU  - Brasfield, F.
AU  - Heaton, R.
AU  - Glinsmann-Gibson, B.
AU  - Crook, L.
AU  - Taetle, R.
AU  - Capizzi, R.
TI  - Stimulation of hematopoiesis by amifostine in patients with myelodysplastic syndrome
JA  - Blood
PY  - 1997///
VL  - 90
SP  - 3364
EP  - 3369
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Liu, T. F.
AU  - Liu, Y.
AU  - He, S.
AU  - Zhang, Z.
AU  - Kligerman, M. M.
TI  - The use of radiation with or without WR-2721 in advanced rectal cancer
JA  - Cancer
PY  - 1992///
VL  - 69
SP  - 2820
EP  - 2825
PB  - Cancer Research Campaign
M3  - 10.1002/1097-0142(19920601)69:11<2820::AID-CNCR2820691130>3.0.CO;2-T
N1  - 10.1002/1097-0142(19920601)69:11<2820::AID-CNCR2820691130>3.0.CO;2-T
UR  - http://dx.doi.org/10.1002/1097-0142(19920601)69:11<2820::AID-CNCR2820691130>3.0.CO;2-T
ER  - 

TY  - JOUR
AU  - Liu, S. C.
AU  - Murley, J. S.
AU  - Woloschak, G.
AU  - Grdina, D. J.
TI  - Repression of c-myc gene expression by the thiol and disulfide forms of the cytoprotector amifostine
JA  - Carcinogenesis
PY  - 1997///
VL  - 18
SP  - 2457
EP  - 2459
PB  - Cancer Research Campaign
M3  - 10.1093/carcin/18.12.2457
N1  - 10.1093/carcin/18.12.2457
UR  - http://dx.doi.org/10.1093/carcin/18.12.2457
ER  - 

TY  - JOUR
AU  - Locatelli, M. C.
AU  - D/'Antona, A.
AU  - Labianca, R.
AU  - Vinci, M.
AU  - Tedeschi, M.
AU  - Carcione, R.
AU  - Corbo, A.
AU  - Venturino, P.
AU  - Luporini, G.
TI  - A phase II study of combination chemotherapy in advanced ovarian carcinoma with cisplatin and cyclophosphamide plus reduced glutathione as potential protective agent against cisplatin toxicity
JA  - Tumori
PY  - 1993///
VL  - 79
SP  - 37
EP  - 39
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - McGuire, W. P.
AU  - Hoskins, W. J.
AU  - Brady, M. F.
AU  - Kucera, P. R.
AU  - Partridge, E. E.
AU  - Look, K. Y.
AU  - Clarke-Pearson, D. L.
AU  - Davidson, M.
TI  - Cyclophosphamide and cisplatin compared with taxol and cisplatin in patients with stage III and stage IV ovarian cancer
JA  - N Engl J Med
PY  - 1996///
VL  - 33
SP  - 1
EP  - 6
PB  - Cancer Research Campaign
M3  - 10.1056/NEJM199601043340101
N1  - 10.1056/NEJM199601043340101
UR  - http://dx.doi.org/10.1056/NEJM199601043340101
ER  - 

TY  - JOUR
AU  - Mangold, D. J.
AU  - Miller, M. A.
AU  - Huelle, B. K.
AU  - Sanchez-Barona, D. O.
AU  - Swynnerton, N. F.
AU  - Flechenstein, L.
AU  - Ludden, T. M.
TI  - Disposition of the radioprotector ethiofos in the rhesus monkey. Influence of route of administration
JA  - Drug Metab Dispos
PY  - 1989///
VL  - 17
SP  - 304
EP  - 310
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Meister, A.
TI  - Selective modification of glutathione metabolism
JA  - Science
PY  - 1983///
VL  - 220
SP  - 472
EP  - 477
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Milas, L.
AU  - Hunter, N.
AU  - Stephens, L. C.
AU  - Peters, L. J.
TI  - Inhibition of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid)
JA  - Cancer Res
PY  - 1984///
VL  - 44
SP  - 5567
EP  - 5569
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Millar, J. L.
AU  - McElwain, T. J.
AU  - Clutterbuck, R. D.
AU  - Wist, E. A.
TI  - The modification of melphalan toxicity in tumour bearing mice by WR-2721
JA  - Am J Clin Oncol
PY  - 1982///
VL  - 5
SP  - 321
EP  - 328
PB  - Cancer Research Campaign
M3  - 10.1097/00000421-198206000-00015
N1  - 10.1097/00000421-198206000-00015
UR  - http://dx.doi.org/10.1097/00000421-198206000-00015
ER  - 

TY  - JOUR
AU  - Mollman, J. E.
AU  - Glover, D. J.
AU  - Hogan, W. M.
AU  - Furman, R. E.
TI  - Cisplatin neuropathy. Risk factors, prognosis, and protection by WR-2721
JA  - Cancer
PY  - 1988///
VL  - 61
SP  - 2192
EP  - 2195
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Montana, G. S.
AU  - Anscher, M. S.
AU  - Mansbach, IICM
AU  - Daly, N.
AU  - Delannes, M.
AU  - Clarke-Pearson, D.
AU  - Gaydica, F.
TI  - Topical application of WR-2721 to prevent radiation-induced proctosigmoiditis
JA  - Cancer
PY  - 1992///
VL  - 69
SP  - 2826
EP  - 2830
PB  - Cancer Research Campaign
M3  - 10.1002/1097-0142(19920601)69:11<2826::AID-CNCR2820691131>3.0.CO;2-8
N1  - 10.1002/1097-0142(19920601)69:11<2826::AID-CNCR2820691131>3.0.CO;2-8
UR  - http://dx.doi.org/10.1002/1097-0142(19920601)69:11<2826::AID-CNCR2820691131>3.0.CO;2-8
ER  - 

TY  - JOUR
AU  - Mori, T.
AU  - Nikaido, O.
AU  - Sugahara, T.
TI  - Dephosphorylation of WR-2721 with mouse tissue homogenates
JA  - Int J Radiat Oncol Biol Phys
PY  - 1984///
VL  - 10
SP  - 1529
EP  - 1531
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Murley, J. S.
AU  - Grdina, D. J.
TI  - The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention
JA  - Carcinogenesis
PY  - 1995///
VL  - 16
SP  - 2699
EP  - 2705
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Murley, J. S.
AU  - Constantinou, A.
AU  - Kamath, N. S.
AU  - Grdina, D. J.
TI  - WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells
JA  - Cell Profil
PY  - 1997///
VL  - 30
SP  - 283
EP  - 294
PB  - Cancer Research Campaign
M3  - 10.1046/j.1365-2184.1997.00092.x
N1  - 10.1046/j.1365-2184.1997.00092.x
UR  - http://dx.doi.org/10.1046/j.1365-2184.1997.00092.x
ER  - 

TY  - JOUR
AU  - Nagy, B.
AU  - Grdina, D. J.
TI  - Protective effects of WR-2721 against bleomycin and nitrogen mustard-induced mutagenicity in V76 cells
JA  - Int J Radiat Oncol Biol Phys
PY  - 1986///
VL  - 12
SP  - 1475
EP  - 1478
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Nagy, B.
AU  - Dale, P. J.
AU  - Grdina, D. J.
TI  - Protection against cis diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by WR-2721
JA  - Cancer Res
PY  - 1986///
VL  - 46
SP  - 1132
EP  - 1135
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Nooijen, P. T.
AU  - Westphal, J. R.
AU  - Eggermont, A. M.
AU  - Schalkwijk, C.
AU  - Max, R.
AU  - De Waal, R. M.
AU  - Ruiter, D. J.
TI  - Endothelial P-selectin expression is reduced an advanced primary melanoma and melanoma metastasis
JA  - Am J Pathol
PY  - 1998///
VL  - 152
SP  - 679
EP  - 682
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Parnis, F. X.
AU  - Coleman, R. E.
AU  - Harper, P. G.
AU  - Pickering, D.
AU  - Topham, C.
AU  - Whittington, J. R.
AU  - Tedeschi, M.
TI  - A randomised double-blind placebo controlled clinical trial assessing the tolerability and efficacy of glutathione as an adjuvant to escalating doses of cisplatin in the treatment of advanced ovarian cancer
JA  - Eur J Cancer
PY  - 1995///
VL  - 31A
SP  - 1721
EP  - 
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Planting, A. S. T.
AU  - Vermorken, J. B.
AU  - Catimel, G.
AU  - De Mulder, P. H. M.
AU  - De Graeff, A.
AU  - Oster, W.
AU  - Hoppener, F.
TI  - Randomized phase II study of cisplatin with and without amifostine in patients with advanced head and neck cancer
JA  - Proc Am Soc Clin Oncol
PY  - 1996///
VL  - 15
SP  - 
EP  - 
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Poplin, E. A.
AU  - LoRusso, P.
AU  - Lokich, J. J.
TI  - Randomized clinical trial of mitomycin-C with or without pretreatment with WR-2721 in patients with advanced colorectal cancer
JA  - Cancer Chemother Pharmacol
PY  - 1994///
VL  - 33
SP  - 415
EP  - 419
PB  - Cancer Research Campaign
M3  - 10.1007/s002800050074
N1  - 10.1007/s002800050074
UR  - http://dx.doi.org/10.1007/s002800050074
ER  - 

TY  - JOUR
AU  - Romero, F. J.
AU  - Segura-Aguilar, J.
AU  - Monsalre, E.
AU  - Hermenegildo, C.
AU  - Nies, E.
AU  - Puertas, F. J.
AU  - Roma, J.
TI  - Antioxidant and glutathione-related enzymatic activities in rat sciatic nerve
JA  - Neurotoxicol Teratol
PY  - 1990///
VL  - 12
SP  - 603
EP  - 605
PB  - Cancer Research Campaign
M3  - 10.1016/0892-0362(90)90069-O
N1  - 10.1016/0892-0362(90)90069-O
UR  - http://dx.doi.org/10.1016/0892-0362(90)90069-O
ER  - 

TY  - JOUR
AU  - Rubin, J. S.
AU  - Wadler, S.
AU  - Beitler, J. J.
AU  - Haynes, H.
AU  - Rozenblit, A.
AU  - McGill, F.
AU  - Goldberg, G.
AU  - Runowicz, C.
TI  - Audiological findings in a phase I protocol investigating the effect of WR-2721, high-dose cisplatin and radiation therapy in patients with locally advanced cervical carcinoma
JA  - J Laryngol Otol
PY  - 1995///
VL  - 109
SP  - 744
EP  - 747
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Sajjan, A. R.
AU  - Hinchigeri, S. B.
AU  - Datta, K. S.
TI  - Multiple forms of [ggr]-glutamyl transpeptidase in human submandibular gland
JA  - Clin Chim Acta
PY  - 1991///
VL  - 197
SP  - 133
EP  - 139
PB  - Cancer Research Campaign
M3  - 10.1016/0009-8981(91)90275-H
N1  - 10.1016/0009-8981(91)90275-H
UR  - http://dx.doi.org/10.1016/0009-8981(91)90275-H
ER  - 

TY  - JOUR
AU  - Schiller, J. H.
AU  - Storer, B.
AU  - Berlin, J.
TI  - Amifostine, cisplatin and vinblastine in metastatic non-small-cell lung cancer; a report of high response rates and prolonged survival
JA  - J Clin Oncol
PY  - 1996///
VL  - 14
SP  - 1913
EP  - 1921
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Schwindt, E. A.
AU  - Collet, A. M.
AU  - Mendez, A. E.
AU  - Cabrini, R. L.
AU  - Itoiz, M. E.
TI  - The first normal oral epithelium which [ggr]-glutamyl transpeptidase activity has been detected
JA  - Histochem J
PY  - 1992///
VL  - 24
SP  - 964
EP  - 968
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Shapiro, C. L.
AU  - Henderson, I. C.
TI  - Late cardiac effects of adjuvant therapy: too soon to tell?
JA  - Ann Oncol
PY  - 1994///
VL  - 5
SP  - 196
EP  - 198
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Shaw, L. M.
AU  - Turrisi, A. T.
AU  - Glover, D. J.
TI  - Human pharmacokinetics of WR-2721
JA  - Int J Radiat Oncol Biol Phys
PY  - 1986///
VL  - 12
SP  - 1501
EP  - 1504
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Shaw, L. M.
AU  - Bonner, H.
AU  - Nakashima, H.
AU  - Lieberman, R.
TI  - Evidence for saturable metabolism
JA  - Proc Am Soc Clin Oncol
PY  - 1994///
VL  - 13
SP  - 
EP  - 
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Shpall, E. J.
AU  - Stemmer, S. M.
AU  - Hami, L.
AU  - Franklin, W. A.
AU  - Shaw, L.
AU  - Bonner, H. S.
AU  - Bearman, S. I.
AU  - Peters, W. P.
AU  - Bast, R. C.
AU  - McCulloch, W.
AU  - Capizzi, R.
AU  - Mitchell, E.
AU  - Schein, P. S.
AU  - Jones, R. B.
TI  - Amifostine (WR-2721) shortens the engraftment period of 4-hydroperoxy-cyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
JA  - Blood
PY  - 1994///
VL  - 83
SP  - 3132
EP  - 3137
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Smoluk, G. D.
AU  - Fahey, R. C.
AU  - Calabro-Jones, P. M.
AU  - Aguilera, J. A.
AU  - Ward, J. F.
TI  - Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection
JA  - Cancer Res
PY  - 1988///
VL  - 48
SP  - 3641
EP  - 3647
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Smyth, I.
AU  - Bowman, A.
AU  - Perren, T.
AU  - Wilkinson, P.
AU  - Prescott, R.
AU  - Quinn, K. J.
AU  - Tedeschi, M.
TI  - Glutathione reduces the toxicity and improves quality of life of women diagnosed with ovarian cancer treated with cisplatin: Results of a double-blind randomised trial
JA  - Ann Oncol
PY  - 1997///
VL  - 8
SP  - 569
EP  - 573
PB  - Cancer Research Campaign
M3  - 10.1023/A:1008211226339
N1  - 10.1023/A:1008211226339
UR  - http://dx.doi.org/10.1023/A:1008211226339
ER  - 

TY  - GEN
AU  - Steinherz, L. J.
AU  - Yahalom, J.
TI  - Cardiac complications of cancer therapy
JA  - Cancer Principles & Practice of Oncology
PY  - 1993///
VL  - 
SP  - 2370
EP  - 2385
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Swain, S. M.
AU  - Whaley, F. S.
AU  - Gerber, M. C.
AU  - Weisberg, S.
AU  - York, M.
AU  - Spicer, D.
AU  - Jones, S. E.
AU  - Wadler, S.
AU  - Desai, A.
AU  - Vogel, C.
AU  - Speyer, J.
AU  - Mittelman, A.
AU  - Reddy, S.
AU  - Pendergrass, K.
AU  - Velez-Garcia, E.
AU  - Ewer, M. S.
AU  - Bianchine, J. R.
AU  - Gams, R. A.
TI  - Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer
JA  - J Clin Oncol
PY  - 1997///
VL  - 15
SP  - 1318
EP  - 1332
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Taylor, C. W.
AU  - Wang, L. M.
AU  - List, A. F.
AU  - Fernandes, D.
AU  - Paine-Murrieta, G. D.
AU  - Johnson, C. S.
AU  - Capizzi, R. L.
TI  - Amifostine protects normal tissues from paclitaxel toxicity while cytotoxicity against tumour cells is maintained
JA  - Eur J Cancer
PY  - 1997///
VL  - 33
SP  - 1693
EP  - 1698
PB  - Cancer Research Campaign
M3  - 10.1016/S0959-8049(97)00221-9
N1  - 10.1016/S0959-8049(97)00221-9
UR  - http://dx.doi.org/10.1016/S0959-8049(97)00221-9
ER  - 

TY  - JOUR
AU  - Thompson, D. C.
AU  - Wyrick, S. D.
AU  - Holbrook, D. J.
AU  - Chaney, S. G.
TI  - HPLC and 31P NMR characterization of the reaction between antitumor platinum agents and the phosphorothioate chemoprotective agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721)
JA  - Biochem Pharmacol
PY  - 1995///
VL  - 50
SP  - 1413
EP  - 1419
PB  - Cancer Research Campaign
M3  - 10.1016/0006-2952(96)84545-X
N1  - 10.1016/0006-2952(96)84545-X
UR  - http://dx.doi.org/10.1016/0006-2952(96)84545-X
ER  - 

TY  - JOUR
AU  - Treskes, M.
AU  - Holwerda, U.
AU  - Klein, I.
AU  - Pinedo, H. M.
AU  - Van der Vijgh, W. J. F.
TI  - The chemical reactivity of the modulating agent WR-2721 (ethiofos) and its main metabolites with the antitumor agents cisplatin and carboplatin
JA  - Biochem Pharmacol
PY  - 1991///
VL  - 42
SP  - 2125
EP  - 2130
PB  - Cancer Research Campaign
M3  - 10.1016/0006-2952(91)90347-8
N1  - 10.1016/0006-2952(91)90347-8
UR  - http://dx.doi.org/10.1016/0006-2952(91)90347-8
ER  - 

TY  - JOUR
AU  - Treskes, M.
AU  - Boven, E.
AU  - Van de Loosdrecht, A. A.
AU  - Wijffels, JFAM
TI  - Effects of the modulating agent WR-2721 on myelotoxicity and antitumour activity in carboplatin-treated mice
JA  - Eur J Cancer
PY  - 1994///
VL  - 30A
SP  - 183
EP  - 187
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Utley, J. F.
AU  - Marlowe, C.
AU  - Waddell, W. J.
TI  - Distribution of 35S-labeled WR-2721 in normal and malignant tissues of the mouse
JA  - Radiat Res
PY  - 1976///
VL  - 68
SP  - 284
EP  - 291
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Valeriote, F.
AU  - Tolen, S.
TI  - Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721
JA  - Cancer Res
PY  - 1982///
VL  - 42
SP  - 4330
EP  - 4331
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Van der Vijgh, W. J.
AU  - Korst, A. E.
TI  - 
JA  - Eur J Cancer
PY  - 1996///
VL  - 32A(4)
SP  - S26
EP  - S30
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Washburn, L. C.
AU  - Rafter, J. J.
AU  - Hayes, R. L.
AU  - Yuhas, J. M.
TI  - Prediction of the effective radioprotective dose of WR-2721 in humans through an interspecies tissue distribution study
JA  - Radiat Res
PY  - 1976///
VL  - 66
SP  - 100
EP  - 105
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Wasserman, T. H.
AU  - Philips, T. L.
AU  - Ross, G.
AU  - Kane, L. J.
TI  - Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721
JA  - Cancer Clin Trials
PY  - 1981///
VL  - 4
SP  - 3
EP  - 6
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Weiss, J. F.
TI  - Pharmacologic approaches to protection against radiation-induced lethality and other damage
JA  - Environ Health Perspect
PY  - 1997///
VL  - 105S
SP  - 1473
EP  - 1478
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Wooley, P. V.
AU  - Ayoob, M. J.
AU  - Smith, F. P.
TI  - Clinical trial of the effect of S-2(3- aminopropylamino)-ethylphosphorothioic acid (WR-2721) (NSC 296961) on the toxicity of cyclophosphamide
JA  - J Clin Oncol
PY  - 1983///
VL  - 5
SP  - 198
EP  - 203
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Yuhas, J. M.
TI  - Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
JA  - Cancer Res
PY  - 1980///
VL  - 40
SP  - 1519
EP  - 1524
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Zunino, F.
AU  - Prates, G.
AU  - Micheloni, A.
AU  - Cavalleti, E.
AU  - Sala, F.
AU  - Tofanetti, O.
TI  - Protective effect of reduced glutathione against cisplatin induced renal and systemic toxicity and its influence on the therapeutic activity of the anti-tumour drug
JA  - Chem Biol Interact
PY  - 1989///
VL  - 70
SP  - 89
EP  - 101
PB  - Cancer Research Campaign
M3  - 10.1016/0009-2797(89)90065-3
N1  - 10.1016/0009-2797(89)90065-3
UR  - http://dx.doi.org/10.1016/0009-2797(89)90065-3
ER  - 

