Short Communication

British Journal of Cancer (1999) 80, 1828–1829. doi:10.1038/sj.bjc.6690606 www.bjcancer.com
Published online 9 July 1999

Risk of cervical cancer is not increased in Chinese carrying homozygous arginine at codon 72 of p53

H Y S Ngan1, V W S Liu1 and S S Liu1

1Department of Obstetrics and Gynaecology, 6/Fl Professorial Block, Queen Mary Hospital, Pokfulam Road, University of Hong Kong, Hong Kong

Received 5 January 1999; Revised 1 February 1999; Accepted 1 February 1999.

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Abstract

Homozygous arginine at codon 72 (HA72) of p53 was found in 22% of normal cervices and 30.0% of cervical cancers and no significant difference was detected between normal and cervical cancer with or without HPV 16/18. There was no correlation between HA72 and risk of cervical cancer in Chinese.

Keywords:

p53 codon 72 polymorphism, cervical cancer, Chinese

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References

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