Short communication

British Journal of Cancer (1999) 80, 67–69. doi:10.1038/sj.bjc.6690322 www.bjcancer.com
Published online 26 March 1999

The human herpesvirus-type 8 is not involved in malignant melanoma

M Deichmann1, M Thome1, M Bock1, A Jäckel1, V Waldmann1 and H Näher1

1Universitäts-Hautklinik Heidelberg, Vobetastrabetae 2, 69115, Heidelberg, Germany

Received 26 June 1998; Revised 3 November 1998; Accepted 11 November 1998.

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Abstract

Malignant melanomas were supposed to harbour the human herpesvirus-type 8 (HHV-8) genome, as melanoma cells were reported to express interleukin-6 and a homologue of interleukin-6 was found in the HHV-8 genome. We therefore investigated 33 primary malignant melanomas by polymerase chain reaction, but could not find this tumorigenic gamma-herpesvirus in any tumour.

Keywords:

malignant melanoma, human herpesvirus-type 8, interleukin-6, polymerase chain reaction

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