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AU  - Bartlett, N. L.
AU  - Lum, B. L.
AU  - Fisher, G. A.
AU  - Brophy, N. A.
AU  - Ehsan, M. N.
AU  - Halsey, J.
AU  - Sikic, B. I.
TI  - Phase I trial of doxorubicin with cyclosporine as a modulator of multidrug resistance
JA  - J Clin Oncol
PY  - 1994///
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PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Bellamy, W. T.
AU  - Peng, Y. M.
AU  - Odeleye, A.
AU  - Ellsworth, L.
AU  - Xu, M. J.
AU  - Grogan, T. M.
AU  - Weinstein, R. S.
TI  - Cardiotoxicity in the SCID mouse following administration of doxorubicin and cyclosporin A
JA  - Anti-Cancer Drugs
PY  - 1995///
VL  - 6
SP  - 736
EP  - 743
PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Colombo, T.
AU  - Zucchetti, M.
AU  - D’Incalci, M.
TI  - Cyclosporin A markedly changes the distribution of doxorubicin in mice and rats
JA  - J Pharmacol Exp Ther
PY  - 1994///
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PB  - Cancer Research Campaign
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AU  - Cordon-Cardo, C.
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AU  - Casals, D.
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AU  - Biedler, J. L.
AU  - Melamed, M. R.
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AU  - Croop, J. M.
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AU  - Arceci, R. J.
AU  - Gros, P.
AU  - Housman, D. E.
TI  - The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues
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PB  - Cancer Research Campaign
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AU  - Dantzig, A. H.
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AU  - Cao, J.
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TI  - Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979
JA  - Cancer Res
PY  - 1996///
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PB  - Cancer Research Campaign
ER  - 

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AU  - De Jong, J.
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AU  - Snabilié, A. M.
AU  - Bast, A.
AU  - van der Vijgh, W. J. F.
TI  - The role of biotransformation in anthracycline-induced cardiotoxicity in mice
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PB  - Cancer Research Campaign
ER  - 

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AU  - Endicott, J. A.
AU  - Ling, V.
TI  - The biochemistry of P-glycoprotein-mediated multidrug resistance
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AU  - Erlichman, C.
AU  - Moore, M.
AU  - Thiessen, J. J.
AU  - Kerr, I. G.
AU  - Walker, S.
AU  - Goodman, P.
AU  - Bjarnason, G.
AU  - DeAngelis, C.
AU  - Bunting, P.
TI  - Phase I pharmacokinetic study of cyclosporin A combined with doxorubicin
JA  - Cancer Res
PY  - 1993///
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PB  - Cancer Research Campaign
ER  - 

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AU  - Giaccone, G.
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AU  - Welink, J.
AU  - Catimel, G.
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AU  - Vermorken, J. B.
AU  - Pinedo, H. M.
TI  - A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors
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PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Gonzalez, O.
AU  - Colombo, T.
AU  - De Fusco, M.
AU  - Imperatori, L.
AU  - Zucchetti, M.
AU  - D’Incalci, M.
TI  - Changes in doxorubicin distribution and toxicity in mice pretreated with the cyclosporin analogue SDZ PSC 833
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PY  - 1995///
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PB  - Cancer Research Campaign
ER  - 

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AU  - Hyafil, F.
AU  - Vergely, C.
AU  - du Vignaud, P.
AU  - Grand-Perret, T.
TI  - In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
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PB  - Cancer Research Campaign
ER  - 

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AU  - Mayer, U.
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AU  - Smit, J. W.
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AU  - van Asperen, J.
AU  - Borst, P.
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TI  - Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by mdr1a P-glycoprotein
JA  - Br J Pharmacol
PY  - 1996///
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PB  - Cancer Research Campaign
ER  - 

TY  - JOUR
AU  - Mayer, U.
AU  - Wagenaar, E.
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AU  - Borst, P.
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PB  - Cancer Research Campaign
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AU  - Mross, K.
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AU  - Gall, H.
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TI  - Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans
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PY  - 1988///
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PB  - Cancer Research Campaign
ER  - 

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AU  - Olson, R. D.
AU  - Mushlin, P. S.
AU  - Brenner, D. E.
AU  - Fleischer, S.
AU  - Cusack, B. J.
AU  - Chang, B. K.
AU  - Boucek, R. J.
TI  - Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol
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PB  - Cancer Research Campaign
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AU  - Schinkel, A. H.
AU  - Smit, J. J. M.
AU  - van Tellingen, O.
AU  - Beijnen, J. H.
AU  - Wagenaar, E.
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AU  - Mol, CAAM
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AU  - Robanus-Maandag, E. C.
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AU  - Borst, P.
TI  - Disruption of the mousemdr1aP-glycoprotein gene leads to a deficiency in the blood–brain barrier and to increased sensitivity to drugs
JA  - Cell
PY  - 1994///
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ER  - 

TY  - JOUR
AU  - Schinkel, A. H.
AU  - Wagenaar, E.
AU  - van Deemter, L.
AU  - Mol, CAAM
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TI  - Absence of the mdr1a P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A
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ER  - 

TY  - JOUR
AU  - Schinkel, A. H.
AU  - Wagenaar, E.
AU  - Mol, CAAM
AU  - van Deemter, L.
TI  - P-glycoprotein in blood–brain barrier of mice influences the brain penetration and pharmacological activity of many drugs
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ER  - 

TY  - JOUR
AU  - Schinkel, A. H.
AU  - Mayer, U.
AU  - Wagenaar, E.
AU  - Mol, CAAM
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AU  - Smit, J. J. M.
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AU  - Zijlmans, JMJM
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TI  - Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins
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TY  - JOUR
AU  - Sparreboom, A.
AU  - van Asperen, J.
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AU  - Tang-Wai, D. F.
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AU  - de Graaf, D.
AU  - Roninson, I. B.
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JA  - Biochemistry
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PB  - Cancer Research Campaign
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AU  - Thiebaut, F.
AU  - Tsuruo, T.
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AU  - Pastan, I.
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TY  - JOUR
AU  - Tsuruo, T.
AU  - Iida, H.
AU  - Tsukagoshi, S.
AU  - Sakurai, Y.
TI  - Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
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AU  - Beijnen, J. H.
AU  - Nooijen, W. J.
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TI  - Altered pharmacokinetics of vinblastine in mdr1a P-glycoprotein-deficient mice
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TY  - JOUR
AU  - Van Asperen, J.
AU  - van Tellingen, O.
AU  - Beijnen, J. H.
TI  - Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography
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PB  - Cancer Research Campaign
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AU  - Wacher, V. J.
AU  - Wu, C-Y
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TI  - Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy
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PB  - Cancer Research Campaign
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AU  - Webster, L. K.
AU  - Cosson, E. J.
AU  - Stokes, K. H.
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