Table of contents

Volume 100, Issue 10
Published online 12 May 2009 (1517-1696)

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Minireviews

Molecular classification of solid tumours: towards pathway-driven therapeutics

C Swanton and C Caldas

Br J Cancer 100: 1517-1522; advance online publication, April 14, 2009; doi:10.1038/sj.bjc.6605031

Targeting HSP90 for cancer therapy

D Mahalingam, R Swords, J S Carew, S T Nawrocki, K Bhalla and F J Giles

Br J Cancer 100: 1523-1529; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605066

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Clinical Studies

Positive lymph node retrieval ratio optimises patient staging in colorectal cancer

S J Moug, J D Saldanha, J R McGregor, M Balsitis and R H Diament

Br J Cancer 100: 1530-1533; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605049

Long-range epigenetic silencing at 2q14.2 affects most human colorectal cancers and may have application as a non-invasive biomarker of disease

R Mayor, L Casadomé, D Azuara, V Moreno, S J Clark, G Capellà and M A Peinado

Br J Cancer 100: 1534-1539; advance online publication, April 21, 2009; doi:10.1038/sj.bjc.6605045

High expression of tumour-associated trypsin inhibitor correlates with liver metastasis and poor prognosis in colorectal cancer

A Gaber, M Johansson, U-H Stenman, K Hotakainen, F Pontén, B Glimelius, A Bjartell, K Jirström and H Birgisson

Br J Cancer 100: 1540-1548; advance online publication, April 21, 2009; doi:10.1038/sj.bjc.6605047

Predictors of survival and toxicity in patients on adjuvant therapy with 5-fluorouracil for colorectal cancer

M Gusella, A C Frigo, C Bolzonella, R Marinelli, C Barile, A Bononi, G Crepaldi, D Menon, L Stievano, S Toso, F Pasini, E Ferrazzi and R Padrini

Br J Cancer 100: 1549-1557; advance online publication, April 21, 2009; doi:10.1038/sj.bjc.6605052

The impact of radiotherapy late effects on quality of life in gynaecological cancer patients

C L Barker, J A Routledge, D J J Farnell, R Swindell and S E Davidson

Br J Cancer 100: 1558-1565; advance online publication, April 21, 2009; doi:10.1038/sj.bjc.6605050

Pattern and quality of care of cancer pain management. Results from the Cancer Pain Outcome Research Study Group

G Apolone, O Corli, A Caraceni, E Negri, S Deandrea, M Montanari and M T Greco on behalf of the Cancer Pain Outcome Research Study Group (CPOR SG) Investigators

Br J Cancer 100: 1566-1574; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605053

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Translational Therapeutics

Inhibition of tyrosine kinase receptors by SU6668 promotes abnormal stromal development at the periphery of carcinomas

P Farace, M Galiè, F Merigo, A Daducci, L Calderan, E Nicolato, A Degrassi, E Pesenti, A Sbarbati and P Marzola

Br J Cancer 100: 1575-1580; advance online publication, April 21, 2009; doi:10.1038/sj.bjc.6605041

Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy

H Xue, C J Field, M B Sawyer, L A Dieleman and V E Baracos

Br J Cancer 100: 1581-1588; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605051

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system

S D Killeen, J H Wang, E J Andrews and H P Redmond

Br J Cancer 100: 1589-1602; doi:10.1038/sj.bjc.6604942

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Molecular Diagnostics

Prostate cancer-derived urine exosomes: a novel approach to biomarkers for prostate cancer

J Nilsson, J Skog, A Nordstrand, V Baranov, L Mincheva-Nilsson, X O Breakefield and A Widmark

Br J Cancer 100: 1603-1607; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605058

Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer

P Barboro, E Repaci, A Rubagotti, S Salvi, S Boccardo, B Spina, M Truini, C Introini, P Puppo, N Ferrari, G Carmignani, F Boccardo and C Balbi

Br J Cancer 100: 1608-1616; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605057

Expression of endoglin (CD105) in cervical cancer

H J Zijlmans, G J Fleuren, S Hazelbag, C F Sier, E J Dreef, G G Kenter and A Gorter

Br J Cancer 100: 1617-1626; advance online publication, April 7, 2009; doi:10.1038/sj.bjc.6605009

Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force

K Beiske, S A Burchill, I Y Cheung, E Hiyama, R C Seeger, S L Cohn, A D J Pearson and K K Matthay

Br J Cancer 100: 1627-1637; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605029

CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion

S Singh, K C Nannuru, A Sadanandam, M L Varney and R K Singh

Br J Cancer 100: 1638-1646; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605055

Activation of Wnt/beta-catenin signalling pathway induces chemoresistance to interferon-alpha/5-fluorouracil combination therapy for hepatocellular carcinoma

T Noda, H Nagano, I Takemasa, S Yoshioka, M Murakami, H Wada, S Kobayashi, S Marubashi, Y Takeda, K Dono, K Umeshita, N Matsuura, K Matsubara, Y Doki, M Mori and M Monden

Br J Cancer 100: 1647-1658; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605064

The use of kallikrein-related peptidases as adjuvant prognostic markers in colorectal cancer

M Talieri, L Li, Y Zheng, D K Alexopoulou, A Soosaipillai, A Scorilas, D Xynopoulos and E P Diamandis

Br J Cancer 100: 1659-1665; advance online publication, April 14, 2009; doi:10.1038/sj.bjc.6605033

Hypoxia-inducible factor-1alpha and -2alpha are expressed in most rectal cancers but only hypoxia-inducible factor-1alpha is associated with prognosis

S Rasheed, A L Harris, P P Tekkis, H Turley, A Silver, P J McDonald, I C Talbot, R Glynne-Jones, J M A Northover and T Guenther

Br J Cancer 100: 1666-1673; doi:10.1038/sj.bjc.6605026

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Genetics and Genomics

TGFBR1 variants TGFBR1 * 6A and Int7G24A are not associated with an increased familial colorectal cancer risk

J Skoglund Lundin, J Vandrovcova, B Song, X Zhou, M Zelada-Hedman, B Werelius, R S Houlston and A Lindblom

Br J Cancer 100: 1674-1679; advance online publication, April 28, 2009; doi:10.1038/sj.bjc.6605054

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer

J Chang-Claude, C B Ambrosone, C Lilla, S Kropp, I Helmbold, D von Fournier, W Haase, M-L Sautter-Bihl, F Wenz, P Schmezer and O Popanda

Br J Cancer 100: 1680-1686; advance online publication, April 14, 2009; doi:10.1038/sj.bjc.6605036

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer

R Shah, P Smith, C Purdie, P Quinlan, L Baker, P Aman, A M Thompson and T Crook

Br J Cancer 100: 1687-1696; doi:10.1038/sj.bjc.6605042

The published online date indicates the date that the issue is published online and is the first official publication date of the issue. Each print issue of BJC is published one week after it has been published online.

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