Web Focus on Human Papillomavirus (HPV)
It is now well established that infection with 'high risk' strains of human papillomavirus (HPV) significantly increases risk of developing cervical cancer. Strains 16 and 18 alone are implicated in ~70% of cervical cancer cases. Recent advances in HPV screening methods and the availability of vaccination have made HPV a "Hot topic" in both research and the media; this web focus brings together a selection of key articles recently published by BJC in this field.
2006
Clinical Study
High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up FREE
L L Villa, R L R Costa, C A Petta, R P Andrade, J Paavonen, O-E Iversen, S-E Olsson, J Høye, M Steinwall, G Riis-Johannessen, A Andersson-Ellstrom, K Elfgren, G von Krogh, M Lehtinen, C Malm, G M Tamms, K Giacoletti, L Lupinacci, R Railkar, F J Taddeo, J Bryan, M T Esser, H L Sings, A J Saah and E Barr
Doi:10.1038/sj.bjc.6603469
2007
Epidemiology
Estimating the long-term impact of a prophylactic human papillomavirus 16/18 vaccine on the burden of cervical cancer in the UK FREE
M Kohli, N Ferko, A Martin, E L Franco, D Jenkins, S Gallivan, C Sherlaw-Johnson and M Drummond
Doi: 10.1038/sj.bjc.6603501
Minireview
Prophylactic HPV vaccines: prospects for eliminating ano-genital cancer FREE
M Stanley
Doi: 10.1038/sj.bjc.6603695
2008
Minireview
HPV and cervical cancer: screening or vaccination? FREE
F X Bosch, X Castellsagué and S de Sanjosé
Doi: 10.1038/sj.bjc.6604146
Genetics and Genomics
Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial FREE
A Sargent, A Bailey, M Almonte, A Turner, C Thomson, J Peto, M Desai, J Mather, S Moss, C Roberts and H C Kitchener on behalf of the ARTISTIC Study Group
Doi: 10.1038/sj.bjc.6604324
Epidemiology
Age-dependent prevalence of 14 high-risk HPV types in the Netherlands: implications for prophylactic vaccination and screening FREE
V M H Coupé, J Berkhof, N W J Bulkmans, P J F Snijders and C J L M Meijer
Doi: 10.1038/sj.bjc.6604162
Clinical Study
Health and economic impact of HPV 16 and 18 vaccination and cervical cancer screening in India FREE
M Diaz, J J Kim, G Albero, S de Sanjosé, G Clifford, F X Bosch and S J Goldie
Doi: 10.1038/sj.bjc.6604462
Epidemiology
Parental attitudes and information needs in an adolescent HPV vaccination programme
R Stretch, S A Roberts, R McCann, D Baxter, G Chambers, H Kitchener and L Brabin
Doi: 10.1038/sj.bjc.6604766
2009
Epidemiology
Risk of cervical abnormality after age 50 in women with previously negative smears
R G Blanks, S M Moss, S Addou, D A Coleman and A J Swerdlow
Doi: 10.1038/sj.bjc.6605069
Epidemiology
Differences in the risk of cervical cancer and human papillomavirus infection by education level FREE
S Franceschi, M Plummer, G Clifford, S de Sanjose, X Bosch, R Herrero, N Muñoz and S Vaccarella for the International Agency for Research on Cancer Multicentric Cervical Cancer Study Groups and the International Agency for Research on Cancer Human Papillomavirus Prevalence Surveys Study Group
Doi: 10.1038/sj.bjc.6605224
