On World Cancer Day 2018, we present some of our top cited content from the last year. This selection reflects developing and ongoing trends in the cancer research community, including liquid biopsies, cancer metabolism, and our growing understanding of the immune system and immunotherapy. We hope you enjoy reading our Editor’s highlights, as we look forward to another year of exciting developments.
To mark the launch of our new Cellular and Molecular Biology section in the British Journal of Cancer, we present a series of articles to highlight our best research and reviews in this area. Edited by Colin Goding (Ludwig Institute for Cancer Research, University of Oxford)
Which of these recent highlights from BJC have you missed?
Access some of our top cited content from the last year of BJC in support of World Cancer Day. We hope you enjoy our latest research into advancements in the field. Please feel free to share these articles with your colleagues.
Immunotherapies have revolutionised therapy for some cancers.
In particular, antibodies that block signals that reduce inhibition of T cell function, have led to complete regressions that are maintained for years, in melanoma and now in bladder cancer and non-small cell lung cancer. Recently, chimeric antigen receptor T cells have produced remarkable responses in patients who have failed multiple other therapies. In parallel with therapeutic trials, many other mechanisms and pathways are being investigated in optimising these treatments.
Many of these areas are covered in this collection of papers and reviews.