Collection on World Cancer Day - Highlights from 2016 and 2017

Which of these recent highlights from BJC have you missed?

Access some of our top cited content from the last year of BJC in support of World Cancer Day. We hope you enjoy our latest research into advancements in the field. Please feel free to share these articles with your colleagues.

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Antibody-drug conjugates—an emerging class of cancer treatment Open

Nikolaos Diamantis and Udai Banerji

Br J Cancer 114: 362-367; advance online publication, January 7, 2016; doi:10.1038/bjc.2015.435

Comparative mutational landscape analysis of patient-derived tumour xenografts

Mariana Brait, Evgeny Izumchenko, Luciane T Kagohara, Samuel Long, Piotr T Wysocki, Brian Faherty, Elana J Fertig, Tin Oo Khor, Elizabeth Bruckheimer, Gilson Baia, Daniel Ciznadija, Ido Sloma, Ido Ben-Zvi, Keren Paz and David Sidransky

Br J Cancer advance online publication, January 24, 2017; doi:10.1038/bjc.2016.450

EGFR mutation detection in circulating cell-free DNA of lung adenocarcinoma patients: analysis of LUX-Lung 3 and 6 Open

Yi-Long Wu, Lecia V Sequist, Cheng-Ping Hu, Jifeng Feng, Shun Lu, Yunchao Huang, Wei Li, Mei Hou, Martin Schuler, Tony Mok, Nobuyuki Yamamoto, Kenneth O'Byrne, Vera Hirsh, Neil Gibson, Dan Massey, Miyoung Kim and James Chih-Hsin Yang

Br J Cancer 116: 175-185; advance online publication, December 22, 2016; doi:10.1038/bjc.2016.420

Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

S Bowyer, P Prithviraj, P Lorigan, J Larkin, G McArthur, V Atkinson, M Millward, M Khou, S Diem, S Ramanujam, B Kong, E Liniker, A Guminski, P Parente, M C Andrews, S Parakh, J Cebon, G V Long, M S Carlino and O Klein

Br J Cancer 114: 1084-1089; advance online publication, April 28, 2016; doi:10.1038/bjc.2016.107

Hallmarks of cancer stem cell metabolism Open

Patricia Sancho, David Barneda and Christopher Heeschen

Br J Cancer 114: 1305-1312; advance online publication, May 24, 2016; doi:10.1038/bjc.2016.152

A circulating miRNA assay as a first-line test for prostate cancer screening

Evgeniya Sharova, Angela Grassi, Anna Marcer, Katia Ruggero, Francesco Pinto, Pierfrancesco Bassi, Paola Zanovello, Filiberto Zattoni, Donna M D'Agostino, Massimo Iafrate and Vincenzo Ciminale

Br J Cancer 114: 1362-1366; advance online publication, May 26, 2016; doi:10.1038/bjc.2016.151

Transforming growth factor β as regulator of cancer stemness and metastasis Open

Claudia Bellomo, Laia Caja and Aristidis Moustakas

Br J Cancer 115: 761-769; advance online publication, August 18, 2016; doi:10.1038/bjc.2016.255

Menopausal hormone therapy and breast cancer: what is the true size of the increased risk? Open

Michael E Jones, Minouk J Schoemaker, Lauren Wright, Emily McFadden, James Griffin, Dawn Thomas, Jane Hemming, Karen Wright, Alan Ashworth and Anthony J Swerdlow

Br J Cancer 115: 607-615; advance online publication, July 28, 2016; doi:10.1038/bjc.2016.231

A phase 3 trial evaluating panitumumab plus best supportive care vs best supportive care in chemorefractory wild-type KRAS or RAS metastatic colorectal cancer Open

Tae Won Kim, Anneli Elme, Zvonko Kusic, Joon Oh Park, Anghel Adrian Udrea, Sun Young Kim, Joong Bae Ahn, Ricardo Villalobos Valencia, Srinivasan Krishnan, Ante Bilic, Nebojsa Manojlovic, Jun Dong, Xuesong Guan, Catherine Lofton-Day, A Scott Jung and Eduard Vrdoljak

Br J Cancer 115: 1206-1214; advance online publication, October 13, 2016; doi:10.1038/bjc.2016.309

Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer FREE

Yvette Drew, Jonathan Ledermann, Geoff Hall, Daniel Rea, Ros Glasspool, Martin Highley, Gordon Jayson, Julieann Sludden, James Murray, David Jamieson, Sarah Halford, Gary Acton, Zoe Backholer, Raffaella Mangano, Alan Boddy, Nicola Curtin and Ruth Plummer

Br J Cancer 114: 723-730; advance online publication, March 22, 2016; doi:10.1038/bjc.2016.41

Tumour microenvironment factors shaping the cancer metabolism landscape Open

Dimitrios Anastasiou

Br J Cancer advance online publication, December 22, 2016; doi:10.1038/bjc.2016.412

Cotargeting of CYP-19 (aromatase) and emerging, pivotal signalling pathways in metastatic breast cancer Open

Stine Daldorff, Randi Margit Ruud Mathiesen, Olav Erich Yri, Hilde Presterud Ødegård and Jürgen Geisler

Br J Cancer 116: 10-20; advance online publication, December 6, 2016; doi:10.1038/bjc.2016.405

Inhibition of histone deacetylases in cancer therapy: lessons from leukaemia Open

Elena Ceccacci and Saverio Minucci

Br J Cancer 114: 605-611; advance online publication, February 23, 2016; doi:10.1038/bjc.2016.36

The clinical implications of gene mutations in chronic lymphocytic leukaemia Open

Davide Rossi and Gianluca Gaidano

Br J Cancer 114: 849-854; advance online publication, March 31, 2016; doi:10.1038/bjc.2016.78