Table 1. The basics of leveraging your intellectual property portfolio

From the following article
Leveraging your biotech intellectual property
Michael B Harlin & Kevin A O'Connor
Published online: 24 April 2008
doi:10.1038/bioe.2008.5

MethodAdvantagesDisadvantages
Out-licensingRaises capitalEngenders fear of out-licensing too early
 Is suitable for early-stage technologyCedes some control over reputation and valuation of technology
 Narrows company focus 
Cross-licensingRemoves blocking patentsRequires giving up exclusive rights
 Can allow collaborationCan allow competition
Selling intellectual property (IP) or royalties owed on itRaises short-term capitalRequires demonstrable financial return
 Narrows company focusDiscounts value of IP
Lending secured by IPMakes use of IP, which may be company's most valuable assetInterest rates obtained do not generally reflect IP value
 Raises nondilutive capitalRisks losing IP upon default