Practice abstract


British Dental Journal 204, 133 - 134 (2008)
Published online: 9 February 2008 | doi:10.1038/bdj.2008.48

Subject Categories: Anaesthesia and sedation | Case reports | Oral pathology

Ulceration of gingival mucosa after topical application of EMLA: report of four cases

M. Franz-Montan1, J. Ranali2, J. C. Ramacciato3, E. D. de Andrade4, M. C. Volpato5 & F. C. Groppo6

  • Reviews evidence with regard to the characteristics and properties of the EMLA cream.
  • Helps the practitioner understand and identify possible toxicity signs after using EMLA.
  • Relates one of the first reports on the direct toxicity of EMLA on the oral mucosa after topical application.


This study reports four cases of mucosa ulceration after a 30-minute application of EMLA (0.3 g) as a topical anaesthetic in dentistry. The subjects returned the next day with a white ulceration and desquamation on the application site. EMLA cream should not be applied to the oral mucosa for 30 minutes.

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  1. Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil
  2. Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil
  3. Sao Leopoldo Mandic Dental School of Campinas, Department of Therapautics
  4. Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil
  5. Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil
  6. Physiological Sciences, Piracicaba Dental School, State University of Campinas, Piracicaba, 13414903, Brazil

Correspondence to: F. C. Groppo6 e-mail: fcgroppo@fop.unicamp.br




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