Research archive : Avian Flu

Nature Publishing Group's unique research archive documents the landmark scientific achievements of the avian flu research community in trying to understand and predict the biology of the H5N1 virus, and develop new and better drugs and vaccines.

Research highlights

Nature
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Published:: 25 July 2007

Keywords:: Antivirals; Molecular Evolution

The evolution of epidemic influenza

Nature Reviews Genetics

Published:: 30 January 2007

Keywords:: Epidemic; Epidemiology; H5n1 Virus; Influenza; Influenza Vaccine; Molecular Evolution; Theoretical Models; Host Defense; Gene Sequence; Neuraminidase

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

Nature Medicine

Published:: 10 September 2006

Keywords:: H5n1 Virus; Molecular Evolution; Mortality; Virulence; Cytokines; Host Defense

Molecular virology: Was the 1918 flu avian in origin?

Nature

Published:: 26 April 2006

Keywords:: Molecular Evolution; Pandemic; Gene Sequence

Molecular virology: Was the 1918 pandemic caused by a bird flu? Was the 1918 flu avian in origin? (Reply)

Nature

Published:: 26 April 2006

Keywords:: Molecular Evolution; Pandemic; Gene Sequence

Influenza and the challenge for immunology

Nature Immunology

Published:: 18 April 2006

Keywords:: Antivirals; Avian Flu Vaccine; Influenza Vaccine

Avian flu: Isolation of drug-resistant H5N1 virus

Nature

Published:: 14 October 2005

Keywords:: Antivirals; Molecular Evolution; Mortality; Gene Sequence

Large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution

Nature

Published:: 05 October 2005

Keywords:: Disease Transmission; Influenza; Molecular Evolution; Gene Sequence; 1918 Spanish Flu

Is China prepared for microbial threats? FREE

There is no bigger acute microbial threat to China, and to the rest of the world, than an influenza pandemic, and no better time to prepare for this eventuality than now. David Ho asks what more China could be doing.

Nature

Published:: 25 May 2005

Keywords:: Chickens; China; Ducks; Epidemiology; H5n1 Virus; Molecular Evolution

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses FREE

Nature Medicine

Published:: 26 August 2002

Keywords:: Avian Flu; Avian Flu Vaccine; H5n1 Virus; Molecular Evolution; Pigs; Cytokines; Host Defense

Lessons from the 1918 influenza

Recent studies of the 1918 influenza virus shed light on the risks of avian influenza virus.

Nature Biotechnology

Keywords:: Disease Transmission; Molecular Evolution; Virulence; Viral Entry; Gene Sequence

Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

Nature

Keywords:: Chickens; Diagnosis; Ducks; Epidemiology; H5n1 Virus; Molecular Evolution; Pandemic; X-ray Crystallography; Viral Entry; Gene Sequence

Bird-flu vaccine

Nature Reviews Immunology
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Keywords:: Avian Flu Vaccine; Molecular Evolution

Extinct 1918 virus comes alive

The 1918 'Spanish' flu that killed 20–50 million people has been recreated from its gene sequence. The virus truly is a nasty beast.

Nature Medicine

Keywords:: Influenza; Molecular Evolution; Pandemic; Virulence

Characterization of the 1918 influenza virus polymerase genes

Nature

Keywords:: H5n1 Virus; Influenza; Molecular Evolution; Pandemic; Gene Sequence; 1918 Spanish Flu

Influenza: lessons from past pandemics, warnings from current incidents

Nature Reviews Microbiology

Touching base

Nature Genetics
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Keywords:: Avian Flu; Disease Transmission; Molecular Evolution; Pandemic; Virulence; X-ray Crystallography; Viral Entry

Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus

Nature Reviews Microbiology

Keywords:: Ducks; Geese; Influenza; Molecular Evolution; Pandemic; Pigs

From lethal virus to life-saving vaccine: developing inactivated vaccines for pandemic influenza

Nature Reviews Microbiology

Keywords:: Avian Flu Vaccine; Influenza Vaccine; Molecular Evolution; Pandemic; Virulence

Profile: Robert Webster FREE

Like the mythological heroine Cassandra, Robert Webster seemed destined to remain a prophet who was never to be believed. His vision has since been validated but, fortunately for the world, his predictions of disaster—an influenza pandemic—have not yet reached the proportions of Greek tragedy.