Table 1: Univariate and multivariate analysis of ImmunoSkew index using Cox proportional hazards model to predict disease-specific survival in HER2 breast cancer patients (n = 110).

From: Biopsy variability of lymphocytic infiltration in breast cancer subtypes and the ImmunoSkew score

 Univariate AnalysisMultivariate Analysis
p-valueHRHR 95% CIp-valueHRHR 95% CI
Node Metastasis0.00018*4.772.10–10.820.0033*3.521.52–8.18
Tumour Size0.0031*2.141.29–3.560.044*1.711.01–2.91
Tumour Grade0.731.120.58–2.160.930.970.49–1.92
ImmunoSkew0.0031*2.581.374.850.040*1.971.023.79
Lymphocytic Infiltrate0.050*0.530.29–1.000.380.730.37–1.46
ImmunoSkew0.022*2.261.124.55
Treatment2.36 × 10−12*4.823.11–7.504.66 × 10−12*4.743.05–7.36
ImmunoSkew0.00027*1.741.292.36
  1. *Statistical significance.