Figure 6 : miR-126 mimics restore high glucose-induced impairment of efferocytosis in RAW 264.7 cells.

From: MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes

Figure 6

(A) Representative fluorescent microscopy images showing reduced macrophage engulfment of apoptotic cells (green) in high glucose treated macrophages. miR-126 mimic transfected macrophages rescue high glucose-induced impairment in efferocytosis. Apoptotic cells were calcein labeled (green) and macrophage nuclei were labeled with DAPI (blue). (B) Quantitation of efferocytosis, n = 3. *P < 0.001 NG vs HG + control mimic, **P < 0.01 HG control mimic vs HG + miR126 mimic).