Figure 4 : Downregulation of miR-126 and corresponding increase in ADAM9 expression in diabetic human failing heart tissue.

From: MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes

Figure 4

(A) Quantitative RT-PCR showing lower miR-126 expression in diabetic human failing heart tissue compared to normal heart tissue (normalized to U6, n = 5, *P < 0.05). (B) A corresponding increase in ADAM9 mRNA in diabetic failing heart tissues (normalized to GAPDH, n = 3, *P < 0.05). (C) Representative immunohistochemistry (IHC) images showing increase in ADAM9 expression in human diabetic failing heart tissue compared to normal human heart tissue.