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IMMUNOMETABOLISM

The metabolic tug of war between HIV and T cells

Nature Metabolism volume 1, pages 653–655 (2019)Cite this article

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The loss of T cell immune function as a result of human immunodeficiency virus (HIV) infection leads to opportunistic infections and certain HIV-associated cancers. Two recent studies shed light on the complex immunometabolic changes during HIV infection and open the door to metabolic treatment options that could ultimately cure HIV.

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Fig. 1: Metabolic requirements for HIV infection and antiviral T cell immunity.

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Authors and Affiliations

  1. BC Children’s Hospital Research Institute, Vancouver, British Columbia, Canada

    Ramon I. Klein Geltink

  2. Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada

    Ramon I. Klein Geltink

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  1. Ramon I. Klein Geltink
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Correspondence to Ramon I. Klein Geltink.

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The author declares no competing interests.

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Klein Geltink, R.I. The metabolic tug of war between HIV and T cells. Nat Metab 1, 653–655 (2019). https://doi.org/10.1038/s42255-019-0091-2

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