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DIABETES

Cell makeover for diabetes therapy

Nature Metabolism volume 1, pages 312–313 (2019)Cite this article

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Patients with severe diabetes rely on insulin injections to control their blood glucose. A study now provides evidence that human cells that normally do not release insulin can be converted into insulin-producing cells that are able to normalize glycaemia in diabetic mice.

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Fig. 1: Reprogramming of human α-cells into β-cells.

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Authors and Affiliations

  1. Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, Neuherberg, Germany

    Mostafa Bakhti & Heiko Lickert

  2. Institute of Stem Cell Research, Helmholtz Zentrum München, Neuherberg, Germany

    Mostafa Bakhti & Heiko Lickert

  3. German Center for Diabetes Research (DZD), Neuherberg, Germany

    Mostafa Bakhti & Heiko Lickert

  4. Technical University of Munich, Medical Faculty, Munich, Germany

    Heiko Lickert

Authors
  1. Mostafa Bakhti
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  2. Heiko Lickert
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Correspondence to Heiko Lickert.

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The authors declare no competing interests.

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Bakhti, M., Lickert, H. Cell makeover for diabetes therapy. Nat Metab 1, 312–313 (2019). https://doi.org/10.1038/s42255-019-0048-5

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