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HOMOGENEOUS CATALYSIS

Shining a light on amine synthesis

Given the abundance of amines in pharmaceutical substances, new strategies for the formation of C–N bonds are highly sought after. Now, using a dual photoredox–copper catalysis system, a method for amine synthesis has been developed.

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Fig. 1: The decarboxylative coupling of aliphatic carboxylic acids and amines.

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Correspondence to Neil K. Garg.

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Barber, J.S., Ippoliti, F.M. & Garg, N.K. Shining a light on amine synthesis. Nat Catal 1, 97–98 (2018). https://doi.org/10.1038/s41929-018-0026-4

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