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DRUG DEVELOPMENT

Microneedle patch drug delivery in the gut

Nature Medicine volume 25, pages 1471–1472 (2019)Cite this article

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A novel oral capsule can deploy microneedle patches that release drugs into the intestinal wall for uptake into the bloodstream as shown in animal studies, thereby avoiding injections.

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Fig. 1: Oral capsule for delivery of biologics via the intestine using microneedle patches.

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Authors and Affiliations

  1. School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA

    Mark R. Prausnitz, Yasmine Gomaa & Wei Li

  2. Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, El-Khartoum Square, Alexandria, Egypt

    Yasmine Gomaa

Authors
  1. Mark R. Prausnitz
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  2. Yasmine Gomaa
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  3. Wei Li
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Corresponding author

Correspondence to Mark R. Prausnitz.

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Competing interests

M.P. is an inventor of patents that have been or may be licensed to companies developing microneedle-based products, is a paid advisor to companies developing microneedle-based products and is a founder/shareholder of companies developing microneedle-based products, including Micron Biomedical. These potential conflicts of interest have been disclosed and are being managed by Georgia Tech and/or Emory University.

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Prausnitz, M.R., Gomaa, Y. & Li, W. Microneedle patch drug delivery in the gut. Nat Med 25, 1471–1472 (2019). https://doi.org/10.1038/s41591-019-0606-0

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