A new report finds that peripheral immunization generates tissue-resident memory CD8+ T cells in the central nervous system that provide robust protection against local infection.
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Kovacs, M.A., Harris, T.H. Long-‘Trm’ protection of the CNS. Nat Immunol 21, 825–826 (2020). https://doi.org/10.1038/s41590-020-0716-3
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DOI: https://doi.org/10.1038/s41590-020-0716-3