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TISSUE RESIDENT T CELLS

Resident memory T cells show that it is never too late to change your ways

Immunological memory is a crucial feature of adaptive immunity. A new report proposes a novel ‘outside-in’ mechanism by which a recall immune response may be initiated from the tissue, rather than secondary lymphoid organs.

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Fig. 1: Models of memory T cell migration.

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Correspondence to Iris K. Gratz or Daniel J. Campbell.

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Gratz, I.K., Campbell, D.J. Resident memory T cells show that it is never too late to change your ways. Nat Immunol 21, 359–360 (2020). https://doi.org/10.1038/s41590-020-0637-1

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