Quantitative mass spectrometry applied to T cell activation reveals key insights into signal-transduction pathways. These data identify selective alterations in the concentration of proteins in activated T cells and detail previously undescribed protein–protein interactions.
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Conley, J.M., Berg, L.J. TCR signaling: it’s all about the numbers. Nat Immunol 20, 1415–1416 (2019). https://doi.org/10.1038/s41590-019-0520-0
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DOI: https://doi.org/10.1038/s41590-019-0520-0