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Plasmacytoid dendritic cells: origin matters

Plasmacytoid dendritic cells (pDCs) are type I interferon–producing cells with antigen-presenting potential. pDC populations are composed of transcriptionally and functionally heterogeneous cellular subsets with distinct hematopoietic precursor origin.

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Fig. 1: Differentiation pathways of antigen-presenting cells (DCs, pDCs and macrophages) in mice.

Marina Corral Spence/Springer Nature

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Correspondence to Markus G. Manz.

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Manz, M.G. Plasmacytoid dendritic cells: origin matters. Nat Immunol 19, 652–654 (2018). https://doi.org/10.1038/s41590-018-0143-x

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