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OPTOGENETICS

Cutting actin with light

Actin cytoskeletal structures are essential for many cellular processes, and cofilin is a key protein for the assembly of these highly dynamic structures. A new cofilin construct enables precise optogenetic control of actin assembly in live cells.

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Fig. 1: Controlling actin turnover through optogenetics.

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Correspondence to Qian Chen.

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Chen, Q. Cutting actin with light. Nat Chem Biol 15, 1133–1134 (2019). https://doi.org/10.1038/s41589-019-0410-7

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