Serious infections were the reason for 14.5% of all hospitalizations among people with gout in the USA in 2015–2016, compared with 8.9% in 1998–2000, according to an analysis of data from the U.S. National Inpatient Sample. From 1998 to 2016, rates of hospitalization due to sepsis increased 19.3-fold, for opportunistic infections increased 2.6-fold and for pneumonia increased 2.2-fold. The overall rate of in-hospital mortality was 10.1% for those with sepsis, 4% for opportunistic infections, 3.1% for pneumonia, 0.6% for skin and soft tissue infection and 0.5% for urinary tract infections.
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Singh, J. A. & Cleveland, J. D. Serious infections in people with gout in the United States: a national study of incidence, time-trends and outcomes. Arthritis Care Res. https://doi.org/10.1002/ACR.24201 (2020)
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Onuora, S. Hospitalization for infection on the rise in gout. Nat Rev Rheumatol 16, 296 (2020). https://doi.org/10.1038/s41584-020-0432-2
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DOI: https://doi.org/10.1038/s41584-020-0432-2