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OSTEOARTHRITIS

Big data boost for osteoarthritis genetics

Nature Reviews Rheumatology volume 14, pages 387–388 (2018)Cite this article

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The largest study to date on the genetics of hip and knee osteoarthritis (OA) has yielded new associations with genes encoding a cytokine, a kinase and a transcriptional repressor, as well as genetic correlations with other diseases. Can these clues help to unravel details of the pathogenesis of OA?

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Author information

Authors and Affiliations

  1. Experimental and Observational Rheumatology, Rheumatology Unit, Instituto de Investigación Sanitaria, Hospital Clínico Universitario de Santiago, Santiago de Compostela, Spain

    Antonio Gonzalez

  2. Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, UK

    Ana M. Valdes

  3. Nottingham NIHR Biomedical Research Centre, Nottingham, UK

    Ana M. Valdes

Authors
  1. Antonio Gonzalez
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  2. Ana M. Valdes
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Correspondence to Antonio Gonzalez.

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The authors declare no competing interests.

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Gonzalez, A., Valdes, A.M. Big data boost for osteoarthritis genetics. Nat Rev Rheumatol 14, 387–388 (2018). https://doi.org/10.1038/s41584-018-0023-7

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