A new study provides direct biological evidence for a prodromal phase of multiple sclerosis (MS), with implications for studying disease aetiology and underscoring the limitations of therapies that solely target inflammation. The findings also suggest an opportunity to apply secondary prevention strategies at the very earliest stages of the disease.
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Acknowledgements
This article was supported (in part) by a Manitoba Research Chair from Research Manitoba, and the Waugh Family Chair in Multiple Sclerosis.
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Marrie, R.A. Mounting evidence for a multiple sclerosis prodrome. Nat Rev Neurol 15, 689–690 (2019). https://doi.org/10.1038/s41582-019-0283-0
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DOI: https://doi.org/10.1038/s41582-019-0283-0
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