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NEURODEGENERATION

New biomarkers of postoperative neurocognitive disorders

Nature Reviews Neurology volume 14, pages 320–321 (2018)Cite this article

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New research has found that anaesthesia and surgery are associated with increased blood levels of two markers of neuronal injury — neurofilament light (NFL) and tau. The findings highlight the neurotoxic effects of anaesthesia and surgery and indicate that tau and NFL could present useful biomarkers for postoperative neurocognitive disorders.

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Authors and Affiliations

  1. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA

    Zhongcong Xie

  2. Department of Psychiatry, Shanghai Tenth People’s Hospital, Anesthesia and Brain Function Research Institute, Tongji University School of Medicine, Shanghai, China

    Yuan Shen

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  1. Zhongcong Xie
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  2. Yuan Shen
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Correspondence to Zhongcong Xie or Yuan Shen.

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The authors declare no competing interests.

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Xie, Z., Shen, Y. New biomarkers of postoperative neurocognitive disorders. Nat Rev Neurol 14, 320–321 (2018). https://doi.org/10.1038/s41582-018-0001-3

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