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DIABETIC KIDNEY DISEASE

Renal outcomes of SGLT2 inhibitors and GLP1 agonists in clinical practice

Nature Reviews Nephrology volume 16, pages 433–434 (2020)Cite this article

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Clinical trials of sodium–glucose cotransporter 2 (SGLT2) inhibitors and glucagon-like peptide 1 (GLP1) receptor agonists have shown beneficial effects of these agents on kidney outcomes in patients with type 2 diabetes mellitus. Two new cohort studies now demonstrate that these findings are generalizable to the broad range of patients seen in clinical practice.

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Fig. 1: Patient cohorts enrolled in clinical trials with SGLT2 inhibitors and GLP1 receptor agonists.

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  1. Clinical Pharmacy and Pharmacology, University of Groningen, Groningen, Netherlands

    Annemarie B. van der Aart-van der Beek & Hiddo J. L. Heerspink

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  1. Annemarie B. van der Aart-van der Beek
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  2. Hiddo J. L. Heerspink
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Correspondence to Hiddo J. L. Heerspink.

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Competing interests

H.L.H. has served as a consultant for AbbVie, Astellas, AstraZeneca, Boehringer Ingelheim, Fresenius, Gilead, Janssen, Merck, Mundipharma, Mitsubishi Tanabe, and Retrophin and has received grant support from AbbVie, AstraZeneca, Boehringer Ingelheim, and Janssen. A.B.v.d.A-v.d.B. declares no competing interests.

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van der Aart-van der Beek, A.B., Heerspink, H.J.L. Renal outcomes of SGLT2 inhibitors and GLP1 agonists in clinical practice. Nat Rev Nephrol 16, 433–434 (2020). https://doi.org/10.1038/s41581-020-0312-7

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