Two recent studies identify factors that accelerate the rate of antimicrobial resistance development.
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Original articles
El Meouche, I. & Dunlop, M. J. Heterogeneity in efflux pump expression predisposes antibiotic-resistant cells to mutation. Science 362, 686–690 (2018)
Ragheb, M. N. et al. Inhibiting the evolution of antibiotic resistance. Mol. Cell https://doi.org/10.1016/j.molcel.2018.10.015 (2019)
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York, A. Reduce your speed. Nat Rev Microbiol 17, 1 (2019). https://doi.org/10.1038/s41579-018-0127-8
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DOI: https://doi.org/10.1038/s41579-018-0127-8