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GUT MICROBIOTA

Precision dietary supplementation based on personal gut microbiota

Over the past decade, many studies have revealed the importance of the gut microbiome in disease development and treatment, including in cancer. Because both host genetics and the gut microbiome can influence host phenotype and treatment outcome, there is an urgent need to develop precision medicine and personalize dietary supplementation based on an individual’s microbiome.

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Fig. 1: The effect of short-chain fatty acids in health and disease.

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Acknowledgements

Y.Y.W. is Professor and Vice Chair for Research in Department of Pathology & Laboratory Medicine at University of California, Davis. This work is supported by grants CA222490 and CA179582 from NCI, NIH. The authors thank Lili Sheng and Julia Ann Wu for their contributions in preparing this manuscript.

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Correspondence to Yu-Jui Yvonne Wan.

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Wan, YJ.Y., Jena, P.K. Precision dietary supplementation based on personal gut microbiota. Nat Rev Gastroenterol Hepatol 16, 204–206 (2019). https://doi.org/10.1038/s41575-019-0108-z

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