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The search for predictive metabolic biomarkers for incident T2DM

Nature Reviews Endocrinology volume 14, pages 444–446 (2018)Cite this article

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A recent metabolomics study of plasma samples from normoglycaemic individuals has identified new predictive biomarkers for type 2 diabetes mellitus. The biomarkers described by the authors demonstrate a potential causal connection between changes in glycine and phenylalanine and incident diabetes mellitus.

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Acknowledgements

The authors’ work was supported, in part, by Innovative Medicines Initiative Joint Undertaking under grant agreement number 115317 (DIRECT), European Institute of Innovation & Technology (EIT) Health Innovation Projects grant DeTecT2D (18428) and the German Federal Ministry of Education and Research (BMBF) to the German Center Diabetes Research (DZD e.V.) grant that was awarded to J.A. E.R.P. holds a Wellcome trust New investigator award (102820/Z/13/Z).

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Authors and Affiliations

  1. Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK

    Ewan Pearson

  2. Institute of Experimental Genetics, Genome Analysis Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

    Jerzy Adamski

  3. Lehrstuhl für Experimentelle Genetik, Technische Universität, München, Germany

    Jerzy Adamski

  4. German Center for Diabetes Research (DZD), München-Neuherberg, Germany

    Jerzy Adamski

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  1. Ewan Pearson
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  2. Jerzy Adamski
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Correspondence to Jerzy Adamski.

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Pearson, E., Adamski, J. The search for predictive metabolic biomarkers for incident T2DM. Nat Rev Endocrinol 14, 444–446 (2018). https://doi.org/10.1038/s41574-018-0045-x

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