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PAEDIATRIC CANCER

Lessons learned from a multicentre clinical trial in Africa

The International Society of Paediatric Oncology (SIOP)–Paediatric Oncology in Developing Countries (PODC) Collaborative Wilms Tumour Africa project delivered treatment in eight centres across five countries in sub-Saharan Africa. Setting up a collaboration like this is easier said than done, and herein we share the lessons we learned along the way.

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References

  1. Israels, T. et al. Clinical trials to improve childhood cancer care and survival in sub-Saharan Africa. Nat. Rev. Clin. Oncol. 10, 599–604 (2013).

    Article  Google Scholar 

  2. Israels, T. & Molyneux, E. M. Paediatric oncology: collaborating in Africa-small steps to sustainable success. Nat. Rev. Clin. Oncol. 11, 691–692 (2014).

    Article  Google Scholar 

  3. Israels, T. et al. SIOP PODC: clinical guidelines for the management of children with Wilms tumour in a low income setting. Pediatr. Blood Cancer 60, 5–11 (2013).

    Article  Google Scholar 

  4. Israels, T. et al. SIOP PODC: recommendations for supportive care of children with cancer in a low-income setting. Pediatr. Blood Cancer 60, 899–904 (2013).

    Article  Google Scholar 

  5. Israels, T. et al. Improved outcome at end of treatment in the collaborative Wilms tumour Africa project. Pediatr. Blood Cancer 65, e26945 (2018).

    Article  Google Scholar 

  6. Paintsil, V. et al. The Collaborative Wilms Tumour Africa Project; baseline evaluation of Wilms tumour treatment and outcome in eight institutes in sub-Saharan Africa. Eur. J. Cancer 51, 84–91 (2015).

    Article  Google Scholar 

  7. Rodriguez-Galindo, C. et al. Toward the cure of all children with cancer through collaborative efforts: pediatric oncology as a global challenge. J. Clin. Oncol. 33, 3065–3073 (2015).

    Article  CAS  Google Scholar 

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Acknowledgements

The authors would like to thank the International Society of Paediatric Oncology (SIOP) and World Child Cancer for their financial support.

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Correspondence to Trijn Israels.

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The authors declare no competing interests.

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https://siop-online.org/project/university-college/

The list of participants and their affiliations appear in Box 1.

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Israels, T., Molyneux, E.M. & the SIOP Africa–PODC Collaborative Wilms Tumour Project Group. Lessons learned from a multicentre clinical trial in Africa. Nat Rev Clin Oncol 16, 211–212 (2019). https://doi.org/10.1038/s41571-018-0121-0

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