The majority of patients undergoing CABG surgery receive a saphenous-vein graft, but a new study provides evidence that use of radial-artery grafts improves clinical outcomes after CABG surgery compared with use of saphenous-vein grafts. A total of 1,036 patients were included in this analysis of six randomized controlled trials that compared radial-artery grafting (534 patients) with saphenous-vein grafting (502 patients). At 5 years of follow-up, the risks of myocardial infarction (HR 0.72; P = 0.04) and of repeat vascularization (HR 0.50; P < 0.001) were significantly lower in the radial-artery graft group than in the saphenous-vein graft group. Use of radial-artery grafts was also associated with a lower risk of occlusion. These findings support the current guidelines, which recommend the use of arterial grafts for CABG surgery.