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CANCER IMMUNOTHERAPY

Smart delivery of vaccines

A strategy to enhance antigen immunogenicity was developed by adsorption of polyethyleneimine on a mesoporous silica microrod vaccine for the presentation of tumour viruses and neoantigens, demonstrating their ability to drive anti-tumour immunity.

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Fig. 1: MSR–PEI vaccines support anti-tumour activity and enhanced survival.

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Correspondence to Cornelis J. M. Melief.

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Melief, C.J.M. Smart delivery of vaccines. Nature Mater 17, 482–483 (2018). https://doi.org/10.1038/s41563-018-0085-6

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