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SYNTHETIC METHODOLOGY

A display of sensitivity

Scientific progress often relies on applying published methodological advances to different problems. With the aim of improving both the uptake and reproducibility of chemical transformations, a new assessment tool has now been developed that provides a clear and easy-to-interpret overview of common factors that affect a synthetic method.

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Fig. 1: A reaction-condition-based sensitivity assessment.

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Correspondence to James J. Douglas.

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Douglas, J.J. A display of sensitivity. Nat. Chem. 11, 683–684 (2019). https://doi.org/10.1038/s41557-019-0302-1

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