News and Views

CANCER NANOMEDICINE

Potent drugless dendrimers

A dendrimer that depletes bioavailable copper as a result of its internal make-up displays powerful anticancer activity in mice, and no observable adverse effects.

  • Subscribe to Nature Biomedical Engineering for full access:

    $99

    Subscribe

Additional access options:

Already a subscriber?  Log in  now or  Register  for online access.

References

  1. 1.

    Tomalia, D. A., Christensen, J. B. & Boas, U. (eds) Dendrimers, Dendrons and Dendritic Polymers (Cambridge Univ. Press, Cambridge, UK, 2012).

  2. 2.

    Mintzer, M. A. & Grinstaff, M. W. Chem. Soc. Rev. 40, 173–190 (2011).

  3. 3.

    Shao, S. et al. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-017-0130-9 (2017).

  4. 4.

    Svenson, S. Chem. Soc. Rev. 44, 4131–4144 (2015).

  5. 5.

    Walter, M. V. & Malkoch, M. Chem. Soc. Rev. 41, 4593–4609 (2012).

  6. 6.

    Gupte, A. & Mumper, R. J. Cancer Treat. Rev. 35, 32–46 (2009).

  7. 7.

    Brady, D. C. et al. Nature 509, 492–496 (2014).

  8. 8.

    Starpharma Successful VivaGel® Phase 3 Results and NDA Planned for rBV http://www.starpharma.com/news/328 (7 August 2017).

Download references

Author information

Affiliations

  1. CNRS, Centre Interdisciplinaire de Nanoscience de Marseille, Aix-Marseille University, UMR 7325, Equipe Labellisée Ligue Contre le Cancer, 163, avenue de Luminy, 13288, Marseille, France

    • Zhenbin Lyu
    •  & Ling Peng

Authors

  1. Search for Zhenbin Lyu in:

  2. Search for Ling Peng in:

Corresponding author

Correspondence to Ling Peng.