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Implanted scaffolds: Pre-ordered vessels halt ischaemia

Implanted scaffolds bearing 3D-printed parallel endothelialized channels restore blood perfusion in ischaemic hind limbs and infarcted hearts in rodents.

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Figure 1: Scaffolds with organized vascular channels rescue ischaemia.

References

  1. Mozaffarian, D. et al. Circulation 133, e38–e360 (2016).

    PubMed  Google Scholar 

  2. Dahl, S. L. M. et al. Sci. Transl. Med. 3, 68ra9 (2011).

    Article  Google Scholar 

  3. Landau, S. et al. Biomaterials 122, 72–82 (2017).

    Article  CAS  Google Scholar 

  4. Mirabella, T. et al. Nat. Biomed. Eng. 1, 0083 (2017).

    Article  Google Scholar 

  5. Tang, Z. C. W., Liao, W.-Y., Tang, A. C. L., Tsai, S.-J. & Hsieh, P. C. H. 32, 75–86 (2011).

  6. Levenberg, S. et al. Nat. Biotechnol. 23, 879–884 (2005).

    Article  CAS  Google Scholar 

  7. Koike, N. et al. Nature 428, 138–139 (2004).

    Article  CAS  Google Scholar 

  8. Koffler, J. et al. Proc. Natl Acad. Sci. USA 108, 14789–14794 (2011).

    Article  CAS  Google Scholar 

  9. Perry, L., Flugelman, M. Y. & Levenberg, S. Mol. Ther. 25, 935–948 (2017).

    Article  CAS  Google Scholar 

  10. Rosenfeld, D. et al. Proc. Natl Acad. Sci. USA 113, 3215–3220 (2016).

    Article  CAS  Google Scholar 

  11. Zhang, B. et al. Nat. Mater. 15, 669–678 (2017).

    Article  Google Scholar 

  12. Miller, J. S. et al. Nat. Mater. 11, 768–774 (2012).

    Article  CAS  Google Scholar 

  13. Baranski, J. D. et al. Proc. Natl Acad. Sci. USA 110, 7586–7591 (2013).

    Article  CAS  Google Scholar 

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Correspondence to Shulamit Levenberg.

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Ben-Shaul, S., Landau, S. & Levenberg, S. Implanted scaffolds: Pre-ordered vessels halt ischaemia. Nat Biomed Eng 1, 0089 (2017). https://doi.org/10.1038/s41551-017-0089

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