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Cancer: Seeing the ebb of a tumour virus

Nature Biomedical Engineering volume 1, Article number: 0059 (2017) Cite this article

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A fluorescent peptide that blocks the dimerization of a protein associated with the Epstein–Barr virus enables the imaging and growth inhibition of tumours attributed to the pathogen.

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Figure 1: Interaction between L2P4 and the putative monomer structure of the EBNA1 DNA-binding domain, as suggested by molecular dynamics simulations.
Figure 2: Viral replication in host cells.

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Authors and Affiliations

  1. John G. Kosowicz, Jaeyeun Lee and Richard F. Ambinder are at the Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA.,

    John G. Kosowicz, Jaeyeun Lee & Richard F. Ambinder

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  1. John G. Kosowicz
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  2. Jaeyeun Lee
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  3. Richard F. Ambinder
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Correspondence to Richard F. Ambinder.

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Kosowicz, J., Lee, J. & Ambinder, R. Cancer: Seeing the ebb of a tumour virus. Nat Biomed Eng 1, 0059 (2017). https://doi.org/10.1038/s41551-017-0059

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