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Drug delivery: Brushing off antigenicity

Conjugation of a diabetes drug with a brush polymer reduces the reactivity of the drug conjugate towards pre-existing polymer antibodies in human plasma and improves the drug's performance in diabetic mice.

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Author information

Affiliations

  1. Kang Choon Lee is at the School of Pharmacy, Sungkyunkwan University, Suwon 16469, Korea.

    • Kang Choon Lee
  2. Seulki Lee is at The Russell H. Morgan Department of Radiology and Radiological Sciences and The Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

    • Seulki Lee

Authors

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Corresponding authors

Correspondence to Kang Choon Lee or Seulki Lee.