We would like to thank Ochieng and his associates for sharing their experience regarding immediate intraocular pressure (IOP) profile after transscleral cyclophotocoagulation with 40 spots at the power of 1500 mW for a duration of 1500 ms [1]. Using distinct laser parameters, could explain the different outcomes of their study compared with ours [2]. The laser setting in our series was the recommended standard protocol [3]. The starting laser parameters were a power of 2000 mW for a duration of 2000 ms, and we used 5–6 laser spots in each quadrant. The power was increased in 250 mW increments until an audible “pop” was heard, and then decreased in 250 mW steps until there was no audible “pop”, then the procedure was continued and completed at that power.
As we noted [2], limited outflow facility reserve could have been a predisposing factor for IOP elevation after transscleral cyclophotocoagulation. All our patients had baseline IOP of 20 mm Hg or more on maximally tolerated medical therapy, which indicates a poor outflow status. In Ochieng et al’s report [1], three patients (8.5%) had a baseline IOP of less than 20 mm Hg, which could be a sign of better outflow and more efficiency in handling the laser-imposed load. They also did not provide information regarding the antiglaucoma medications [1]. A study with a long-term follow up using their suggested protocol may support it as an alternative to the standard protocol.
References
Ochieng L, Niyadurupola N, Broadway D, Eke T. Comment on: 'Immediate IOP elevation after transscleral cyclophotocoagulation' Eye (Lond). 2018; epub ahead of print https://doi.org/10.1038/s41433-018-0034-2.
Razeghinejad MR, Hamid A, Nowroozzadeh MH. Immediate IOP elevation after transscleral cyclophotocoagulation. Eye (Lond). 2017;31(8):1249–50.
Pastor SA, Singh K, Lee DA, Juzych MS, Lin SC, Netland PA, et al. Cyclophotocoagulation: a report by the American Academy of Ophthalmology. Ophthalmology. 2001;108(11):2130–8.
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Razeghinejad, M.R., Hamid, A. & Nowroozzadeh, M.H. Response to: 'Comment on: 'Immediate IOP elevation after transscleral cyclophotocoagulation'. Eye 32, 1289 (2018). https://doi.org/10.1038/s41433-018-0036-0
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DOI: https://doi.org/10.1038/s41433-018-0036-0