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Crucial role of histone deacetylase SIRT1 in myeloid-derived suppressor cell-mediated reprogramming of CD4+ T-cell differentiation

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Acknowledgements

The authors’ research is supported by grants from the National Natural Science Foundation for Key Programs of China (31730024, G.L.) and the National Natural Science Foundation for General Programs of China (31671524, G.L.).

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L.D., Y.B., A.J., and Q.Y. designed and conducted the experiment with cells and mice and analyzed the data; Y.X.W., Y.F.W., Q.L.Y., Y.C., Y.H., R.L., and Y.L. participated in discussions; L.D. and Y.B. contributed to writing the paper; and G.L. developed the concept, designed and conducted the experiments, analyzed data, wrote the paper, and provided overall direction.

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Correspondence to Guangwei Liu.

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Dong, L., Bi, Y., Jia, A. et al. Crucial role of histone deacetylase SIRT1 in myeloid-derived suppressor cell-mediated reprogramming of CD4+ T-cell differentiation. Cell Mol Immunol 17, 785–787 (2020). https://doi.org/10.1038/s41423-020-0419-6

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