Sturrock A, Preshaw P, Hayes C, Wilkes S. Perceptions and attitudes of patients towards medication-related osteonecrosis of the jaw (MRONJ): a qualitative study in England. BMJ Open 2019; 9: e024376. DOI: 10.1136/bmjopen-2018-024376.

MRONJ has a significant detrimental impact on quality of life, yet appropriate preventative education is not apparent. Effective interprofessional patient education and prevention to mitigate against the risk of developing MRONJ is required.

This study explored the impact of medication-related osteonecrosis of the jaw (MRONJ) on quality of life and considered the perceptions of patients towards a multidisciplinary approach. Twenty-three patients in primary care general medical practices and secondary care dental services in England were interviewed using qualitative semi-structured interviews. Of those interviewed, six had MRONJ, 13 were taking prescribed bisphosphonates, four had osteoporosis but were not currently taking any medication. Patients felt that MRONJ had a significant negative impact on their quality of life including physical, psychological and social impacts. There was also poor knowledge of the recommended preventive strategies. Patients demonstrated positive attitudes towards a multidisciplinary approach to care; but perceived prescribers as having the key role in articulating risk.